Cat: PA2000-1268

Recombinant Human MAP9 Protein,His

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Analytical Data

  • Gene name

    MAP9

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    MAP9;ASAP;Microtubule-associated Protein 9

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q49MG5

  • Expression Region

    2-647aa

  • AA Sequence

    SDEVFSTTL AYTKSPKVTK RTTFQDELIR AITARSARQR SSEYSDDFDS DEIVSLGDFS DTSADENSVN KKMNDFHISD DEEKNPSKLL FLKTNKSNGN ITKDEPVCAI KNEEEMAPDG CEDIVVKSFS ESQNKDEEFE KDKIKMKPKP RILSIKSTSS AENNSLDTDD HFKPSPRPRS MLKKKSHMEE KDGLEDKETA LSEELELHSA PSSLPTPNGI QLEAEKKAFS ENLDPEDSCL TSLASSSLKQ ILGDSFSPGS EGNASGKDPN EEITENHNSL KSDENKENSF SADHVTTAVE KSKESQVTAD DLEEEKAKAE LIMDDDRTVD PLLSKSQSIL ISTSATASSK KTIEDRNIKN KKSTNNRASS ASARLMTSEF LKKSSSKRRT PSTTTSSHYL GTLKVLDQKP SQKQSIEPDR ADNIRAAVYQ EWLEKKNVYL HEMHRIKRIE SENLRIQNEQ KKAAKREEAL ASFEAWKAMK EKEAKKIAAK KRLEEKNKKK TEEENAARKG EALQAFEKWK EKKMEYLKEK NRKEREYERA KKQKEEETVA EKKKDNLTAV EKWNEKKEAF FKQKEKEKIN EKRKEELKRA EKKDKDKQAI NEYEKWLENK EKQERIERKQ KKRHSFLESE ALPPWSPPSR TVFAKVF

  • Molecular Weight

    74.2 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

MAP9, or Microtubule-Associated Protein 9, is a crucial component in the study of cellular dynamics and microtubule organization. As a member of the MAP family, MAP9 is known to interact with tubulin, stabilizing microtubules and facilitating their assembly during the cell cycle. Research has indicated that MAP9 plays a vital role in cell division, particularly in processes such as spindle formation and chromosomal alignment. Abnormalities in MAP9 expression or function have been linked to various diseases, including cancer, where altered microtubule dynamics can lead to uncontrolled cell proliferation and migration. Additionally, MAP9's involvement in neurogenesis and neuronal stability suggests its potential significance in neurodevelopmental disorders. Recent advances in recombinant protein technology have enabled the production of MAP9 for detailed structural and functional analysis, allowing researchers to explore its interaction with other cellular components and its role in microtubule-associated processes. Understanding the mechanisms through which MAP9 operates can provide insights into the fundamental aspects of cell biology and disease mechanisms, making it a crucial target for further investigation in both basic and applied research contexts.

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