Analytical Data
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Gene name
SNRPD2
- Application
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Alternative Names
SNRPD2;SNRPD1;Small nuclear ribonucleoProtein Sm D2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P62316
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Expression Region
1-118aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MSLLNKPKSE MTPEELQKRE EEEFNTGPLS VLTQSVKNNT QVLINCRNNK KLLGRVKAFD RHCNMVLENV KEMWTEVPKS GKGKKKSKPV NKDRYISKMF LRGDSVIVVL RNPLIAGK
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Molecular Weight
16 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SNRPD2, a component of the small nuclear ribonucleoprotein (snRNP) complex, plays a crucial role in pre-mRNA splicing, a fundamental process that influences gene expression and protein diversity in eukaryotic cells. Research on SNRPD2 has gained momentum due to its involvement in various cellular mechanisms, including RNA processing and the regulation of gene expression. Mutations or dysregulation of SNRPD2 have been associated with several diseases, including cancer and genetic disorders, making it a potential biomarker and therapeutic target. Understanding the structure and function of the SNRPD2 protein can provide insight into splicing mechanisms and the broader implications of snRNPs in cellular homeostasis. The study of recombinant SNRPD2 protein is essential to elucidate its biochemical properties and interactions within the spliceosome, contributing to our understanding of splicing-related pathologies. The advances in recombinant protein technology allow for the production of SNRPD2 in controlled environments, facilitating the exploration of its functional dynamics and interactions with other splicing factors, thereby paving the way for novel therapeutic strategies aimed at correcting splicing defects.
