Analytical Data
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基因名
SNAPC1
- Application
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别名
SNAPC3;SNAP50;snRNA-activating Protein complex subunit 3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q16533
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表达区间
1-368aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGSMGTPPGLQTDCEALLSRFQETDSVRFE DFTELWRNMKFGTIFCGRMRNLEKNMFTKEALALAWRYFLPPYTFQIRVG ALYLLYGLYNTQLCQPKQKIRVALKDWDEVLKFQQDLVNAQHFDAAYIFR KLRLDRAFHFTAMPKLLSYRMKKKIHRAEVTEEFKDPSDRVMKLITSDVL EEMLNVHDHYQNMKHVISVDKSKPDKALSLIKDDFFDNIKNIVLEHQQWH KDRKNPSLKSKTNDGEEKMEGNSQETERCERAESLAKIKSKAFSVVIQAS KSRRHRQVKLDSSDSDSASGQGQVKATRKKEKKERLKPAGRKMSLRNKGN VQNIHKEDKPLSLSMPVITEEEENESLSGTEFTASKKRRKH
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分子量
45 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SNAPC1, or Small Nuclear RNA Activating Protein Complex 1, is a crucial component of the small nuclear ribonucleoprotein (snRNP) complex, playing a pivotal role in the maturation and processing of precursor messenger RNA. Research on SNAPC1 has gained prominence due to its essential function in the transcription regulation of small nuclear RNAs, particularly those involved in spliceosome assembly. The proper functioning of SNAPC1 is vital for maintaining cellular homeostasis, as disruptions in its activity can lead to aberrant gene expression and have been implicated in various diseases, including cancer. Recent studies have focused on understanding the structural properties and molecular mechanisms of SNAPC1, aiming to elucidate how it interacts with other components of the spliceosomal machinery. Insights into SNAPC1's role in RNA processing not only enhance our comprehension of fundamental biological processes but also open avenues for therapeutic interventions targeting its dysfunctions. As such, SNAPC1 serves as a significant model in the broader fields of molecular biology and genetics, warranting continued investigation into its diverse functions and regulatory pathways.
