Cat: PA2000-1244

Recombinant Human MAP1S Protein,His

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Analytical Data

  • Gene name

    MAP1S

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    MAP1S;BPY2IP1;C19orf5;MAP8;Microtubule-associated Protein 1S

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q66K74

  • Expression Region

    794-1053aa

  • AA Sequence

    LSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVSATPPKSPVYLDLAYLPSGSSAHLVDEEFFQRVRALCYVISGQDQRKEEGMRAVLDALLASKQHWDRDLQVTLIPTFDSVAMHTWYAETHARHQALGITVLGSNSMVSMQDDAFP

  • Molecular Weight

    31.7 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

MAP1S, or Microtubule-Associated Protein 1S, is a crucial protein involved in various cellular processes, particularly in the regulation of microtubule dynamics and cellular structure. As a member of the MAP family, MAP1S plays a significant role in neuronal development, axon guidance, and synaptic function. Research has indicated that MAP1S is implicated in several neurodevelopmental disorders and neurodegenerative diseases, highlighting its importance in maintaining neuronal integrity. The study of recombinant MAP1S protein offers valuable insights into its functional properties, enabling researchers to dissect its role in microtubule stability and interaction with other cellular components. Furthermore, understanding the biochemical and biophysical characteristics of recombinant MAP1S can aid in elucidating its mechanisms of action and potential therapeutic targets for related disorders. This research area has gained momentum due to advances in recombinant protein technologies, allowing for the production and characterization of MAP1S in vitro. Exploring the implications of MAP1S in cellular signaling pathways and its interactions with other proteins facilitates a deeper understanding of its contributions to cell biology and disease pathology. Overall, the investigation of recombinant MAP1S protein is a promising field that may lead to novel insights into its biological functions and potential clinical applications in combating neurodevelopmental and neurodegenerative conditions.

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