Analytical Data
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Gene name
SLC51B
- Application
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Alternative Names
SLC51B;OSTB;Organic solute transporter subunit beta
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q86UW2
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Expression Region
57-128aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSRSIQASR KEKMQPPEKE TPEVLHLDEA KDHNSLNNLR ETLLSEKPNL AQVELELKER DVLSVFLPDV PETES
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Molecular Weight
11 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The SLC51B protein, also known as the steroid-sulfatase transporter, is a member of the solute carrier (SLC) family of proteins responsible for the transport of various molecules across cell membranes. Understanding SLC51B is significant because it plays a crucial role in steroid hormone metabolism and the regulation of bile acids, which are essential for digestion and absorption of dietary fats. Dysregulation or mutations in the SLC51B gene have been implicated in various metabolic disorders and diseases, including liver dysfunction and certain cancers. Recent research has focused on the biophysical characteristics and functional mechanisms of SLC51B, particularly how it interacts with sulfate and steroid hormones. Additionally, investigations into its expression patterns in different tissues have revealed its potential role in drug metabolism and detoxification processes. This research emphasizes the necessity to explore SLC51B's functions and interactions further to uncover its biological significance and potential therapeutic targets. Overall, the study of SLC51B is vital for enhancing our understanding of metabolic regulation and developing novel strategies for treating related disorders.
