Analytical Data
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Gene name
ACOT6
- Application
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Alternative Names
ACOT6; C14orf42Putative acyl-coenzyme A thioesterase 6; Putative acyl-CoA thioesterase 6; EC 3.1.2.
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q3I5F7
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Expression Region
1-207aa
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AA Sequence
MLQHPKVKGP SIALLGFSKG GDLCLSMASF LKGITATVLI NACVANTVAP LHYKDMIIPK LVDDLGKVKI TKSGFLTFMD TWSNPLEEHN HQSLVPLEKA QVPFLFIVGM DDQSWKSEFY AQIASERLQA HGKERPQIIC YPETGHCIDP PYFPPSRASV HAVLGEAIFY GGEPKAHSKA QVDAWQQIQT FFHKHLNGKK SVKHSKI
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ACOT6, a member of the acyl-CoA thioesterase family, is involved in the regulation of acyl-CoA levels and fatty acid metabolism. Recent studies have highlighted its potential role in various metabolic pathways and diseases, particularly metabolic disorders and cancer. ACOT6 catalyzes the hydrolysis of acyl-CoA to free fatty acids and coenzyme A, influencing lipid metabolism and energy homeostasis. Its expression levels have been shown to vary across different tissues and physiological conditions, suggesting a tissue-specific regulatory function. Understanding the structure and function of ACOT6 can provide insights into its involvement in metabolic regulation and its potential as a therapeutic target. Researchers are focusing on characterizing the recombinant form of ACOT6 to investigate its enzymatic activity and substrate specificity, aiming to elucidate its role in metabolic diseases. The recombinant protein can serve as a valuable tool for biochemical assays, enabling further studies on its interactions with lipid substrates and inhibitors. The outcomes of this research may pave the way for innovative approaches to modulate fatty acid metabolism, with implications for treating obesity, diabetes, and other related disorders. Thus, ACOT6 represents a compelling focus for future research in metabolic biochemistry and therapies targeting metabolic diseases.
