Analytical Data
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Gene name
ABHD8
- Application
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Alternative Names
ABHD8Protein ABHD8; EC 3.-.-.-; Alpha/beta hydrolase domain-containing Protein 8
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96I13
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Expression Region
1-439aa
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AA Sequence
MLTGVTDGIF CCLLGTPPNA VGPLESVESS DGYTFVEVKP GRVLRVKHAG PAPAAAPPPP SSASSDAAQG DLSGLVRCQR RITVYRNGRL LVENLGRAPR ADLLHGQNGS GEPPAALEVE LADPAGSDGR LAPGSAGSGS GSGSGGRRRR ARRPKRTIHI DCEKRITSCK GAQADVVLFF IHGVGGSLAI WKEQLDFFVR LGYEVVAPDL AGHGASSAPQ VAAAYTFYAL AEDMRAIFKR YAKKRNVLIG HSYGVSFCTF LAHEYPDLVH KVIMINGGGP TALEPSFCSI FNMPTCVLHC LSPCLAWSFL KAGFARQGAK EKQLLKEGNA FNVSSFVLRA MMSGQYWPEG DEVYHAELTV PVLLVHGMHD KFVPVEEDQR MAEILLLAFL KLIDEGSHMV MLECPETVNT LLHEFLLWEP EPSPKALPEP LPAPPEDKK
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Molecular Weight
47.3 KDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ABHD8 (Alpha/Beta Hydrolase Domain Containing 8) is a member of the serine hydrolase family, which has garnered significant interest in recent years due to its potential roles in various biological processes and disease mechanisms. Research has indicated that ABHD8 is involved in lipid metabolism and signaling pathways, influencing cellular functions such as inflammation, neurochemistry, and energy homeostasis. It has also been implicated in the regulation of endocannabinoid levels, which play critical roles in the central nervous system. The recombinant protein of ABHD8 is particularly valuable for studying its enzymatic activity, substrate specificity, and the regulatory mechanisms by which it influences cellular pathways. Additionally, understanding the structure and function of ABHD8 can pave the way for developing therapeutic strategies targeting diseases linked to dysregulated lipid metabolism, such as obesity, diabetes, and neurodegenerative disorders. As a result, the generation and characterization of ABHD8 recombinant protein are critical for elucidating its biological functions and potential as a drug target in therapeutic applications.
