Analytical Data
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Gene name
NUDT6
- Application
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Alternative Names
NUDT6; FGF2AS; Nucleoside diphosphate-linked moiety X motif 6; Nudix motif 6; EC 3.6.1.-; Antisense basic fibroblast growth factor; Protein GFG
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P53370
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Expression Region
1-316 aa
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AA Sequence
MRQPLSWGRW RAMLARTYGP GPSAGYRWAS GAQGYVRNPP VGACDLQGEL DRFGGISVRL ARLDALDRLD AAAFQKGLQA AVQQWRSEGR TAVWLHIPIL QSRFIAPAAS LGFCFHHAES DSSTLTLWLR EGPSRLPGYA SHQVGVAGAV FDESTRKILV VQDRNKLKNM WKFPGGLSEP EEDIGDTAVR EVFEETGIKS EFRSVLSIRQ QHTNPGAFGK SDMYIICRLK PYSFTINFCQ EECLRCEWMD LNDLAKTENT TPITSRVARL LLYGYREGFD KIDLTVEELP AVYTGLFYKL YHKELPENYK TMKGID
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Molecular Weight
35.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NUDT6, known as Nudix hydrolase 6, is a member of the Nudix hydrolase family, which plays a critical role in cellular nucleotide metabolism by hydrolyzing various nucleotide derivatives. Research into NUDT6 is primarily driven by its potential implications in cellular processes such as signal transduction, energy homeostasis, and stress response. It has been suggested that NUDT6 may be involved in the regulation of RNA and DNA metabolism by modulating levels of specific substrates, including nucleoside diphosphates and triphosphates. Given its enzymatic activities, NUDT6's dysfunction may be associated with various diseases, including cancer and neurodegenerative disorders, highlighting its importance as a therapeutic target. As a result, understanding the structure, function, and regulation of NUDT6 is essential for elucidating its biological significance and exploring its potential applications in biotechnology and medicine. Recent studies have focused on the recombinant expression of NUDT6 to further characterize its enzymatic properties and interaction with substrates, providing insights into its precise role in cellular physiology and disease mechanisms. Through these investigations, researchers aim to develop novel strategies for targeting NUDT6 in disease modulation and treatment, underscoring its relevance in both fundamental research and biopharmaceutical development.
