Analytical Data
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Gene name
ABHD1
- Application
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Alternative Names
ABHD1; LABH1; Protein ABHD1; Alpha/beta hydrolase domain-containing Protein 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96SE0
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Expression Region
1-405aa
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AA Sequence
MLSSFLSPQNGTWADTFSLLLALAVALYLGYYWACVLQRPRLVAGPQFLAFLEPHCSITTETFYPTLWCFEGRLQSIFQVLLQSQPLVLYQSDILQTPDGGQLLLDWAKQPDSSQDPDPTTQPIVLLLPGITGSSQETYVLHLVNQALRDGYQAVVFNNRGCRGEELRTHRAFCASNTEDLETVVNHIKHRYPQAPLLAVGISFGGILVLNHLAQARQAAGLVAALTLSACWDSFETTRSLETPLNSLLFNQPLTAGLCQLVERNRKVIEKVVDIDFVLQARTIRQFDERYTSVAFGYQDCVTYYKAASPRTKIDAIRIPVLYLSAADDPFSPVCALPIQAAQHSPYVALLITARGGHIGFLEGLLPWQHWYMSRLLHQYAKAIFQDPEGLPDLRALLPSEDRNS
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Molecular Weight
45.2 KDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ABHD1 (alpha/beta hydrolase domain containing 1) is a member of the serine hydrolase family, and its significance has been increasingly recognized in biomedical research, particularly in the context of lipid metabolism and neurobiology. The enzyme is implicated in the hydrolysis of bioactive lipids, including signaling molecules that play crucial roles in various physiological processes. Dysregulation of ABHD1 has been linked to several diseases, including neurodegenerative disorders and metabolic syndromes. Consequently, the study of ABHD1 recombinant protein has attracted attention as a potential therapeutic target and as a tool to better understand its biochemical pathways. Researchers are particularly interested in characterizing the enzymatic activity, substrate specificity, and regulatory mechanisms of ABHD1. Through the expression and purification of recombinant ABHD1, scientists aim to elucidate its functional roles in lipid signaling and explore its potential implications in disease mechanisms. This research not only provides insights into the enzyme's biological significance but also aids in the development of small molecule inhibitors that could modulate ABHD1 activity for therapeutic purposes. Overall, the comprehensive study of ABHD1 recombinant protein represents a promising avenue for advancing our understanding of lipid biology and developing novel strategies for intervention in related disorders.
