Analytical Data
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基因名
ABHD7
- Application
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别名
EPHX4; ABHD7; EH4; EPHXRP; Epoxide hydrolase 4; Abhydrolase domain-containing Protein 7
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8IUS5
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表达区间
1-362aa
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氨基酸序列
MARLRDCLPRLMLTLRSLLFWSLVYCYCGLCASIHLLKLLWSLGKGPAQTFRRPAREHPPACLSDPSLGTHCYVRIKDSGLRFHYVAAGERGKPLMLLLHGFPEFWYSWRYQLREFKSEYRVVALDLRGYGETDAPIHRQNYKLDCLITDIKDILDSLGYSKCVLIGHDWGGMIAWLIAICYPEMVMKLIVINFPHPNVFTEYILRHPAQLLKSSYYYFFQIPWFPEFMFSINDFKVLKHLFTSHSTGIGRKGCQLTTEDLEAYIYVFSQPGALSGPINHYRNIFSCLPLKHHMVTTPTLLLWGENDAFMEVEMAEVTKIYVKNYFRLTILSEASHWLQQDQPDIVNKLIWTFLKEETRKKD
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分子量
42.3 KDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ABHD7 (Alpha/Beta Hydrolase Domain 7) is a member of the serine hydrolase family, and it has garnered attention in recent years due to its potential roles in various biological processes and diseases. Initially, ABHD7 was identified as a protein involved in lipid metabolism, particularly in the hydrolysis of bioactive lipids that play crucial roles in cell signaling and membrane dynamics. Research has indicated that ABHD7 may be implicated in neurodegenerative diseases, including Alzheimer’s disease, where changes in lipid metabolism are observed. Additionally, ABHD7 has been linked to the regulation of cellular stress responses and apoptosis, further highlighting its significance in cell survival and function. As a hydrolase enzyme, ABHD7 has also emerged as a potential target for therapeutic interventions, particularly in cancer, where altered lipid metabolism is a hallmark of tumor progression. Understanding the structure and function of ABHD7 through recombinant protein studies can provide insights into its enzymatic mechanisms and interactions with lipid substrates. This knowledge can facilitate the development of specific inhibitors or modulators that could be harnessed in disease treatment. Overall, the study of ABHD7 not only enhances our understanding of lipid metabolism but also opens new avenues for biomedical research and therapeutic development.
