Analytical Data
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Gene name
ABHD7
- Application
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Alternative Names
EPHX4; ABHD7; EH4; EPHXRP; Epoxide hydrolase 4; Abhydrolase domain-containing Protein 7
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8IUS5
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Expression Region
1-362aa
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AA Sequence
MARLRDCLPRLMLTLRSLLFWSLVYCYCGLCASIHLLKLLWSLGKGPAQTFRRPAREHPPACLSDPSLGTHCYVRIKDSGLRFHYVAAGERGKPLMLLLHGFPEFWYSWRYQLREFKSEYRVVALDLRGYGETDAPIHRQNYKLDCLITDIKDILDSLGYSKCVLIGHDWGGMIAWLIAICYPEMVMKLIVINFPHPNVFTEYILRHPAQLLKSSYYYFFQIPWFPEFMFSINDFKVLKHLFTSHSTGIGRKGCQLTTEDLEAYIYVFSQPGALSGPINHYRNIFSCLPLKHHMVTTPTLLLWGENDAFMEVEMAEVTKIYVKNYFRLTILSEASHWLQQDQPDIVNKLIWTFLKEETRKKD
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Molecular Weight
42.3 KDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ABHD7 (Alpha/Beta Hydrolase Domain 7) is a member of the serine hydrolase family, and it has garnered attention in recent years due to its potential roles in various biological processes and diseases. Initially, ABHD7 was identified as a protein involved in lipid metabolism, particularly in the hydrolysis of bioactive lipids that play crucial roles in cell signaling and membrane dynamics. Research has indicated that ABHD7 may be implicated in neurodegenerative diseases, including Alzheimer’s disease, where changes in lipid metabolism are observed. Additionally, ABHD7 has been linked to the regulation of cellular stress responses and apoptosis, further highlighting its significance in cell survival and function. As a hydrolase enzyme, ABHD7 has also emerged as a potential target for therapeutic interventions, particularly in cancer, where altered lipid metabolism is a hallmark of tumor progression. Understanding the structure and function of ABHD7 through recombinant protein studies can provide insights into its enzymatic mechanisms and interactions with lipid substrates. This knowledge can facilitate the development of specific inhibitors or modulators that could be harnessed in disease treatment. Overall, the study of ABHD7 not only enhances our understanding of lipid metabolism but also opens new avenues for biomedical research and therapeutic development.
