Analytical Data
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基因名
SIKE1
- Application
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别名
SIKE1;SIKE;Suppressor of IKBKE 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BRV8
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表达区间
1-207aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMSCTIEK ILTDAKTLLE RLREHDAAAE SLVDQSAALH RRVAAMREAG TALPDQYQED ASDMKDMSKY KPHILLSQEN TQIRDLQQEN RELWISLEEH QDALELIMSK YRKQMLQLMV AKKAVDAEPV LKAHQSHSAE IESQIDRICE MGEVMRKAVQ VDDDQFCKIQ EKLAQLELEN KELRELLSIS SESLQARKEN SMDTASQAIK
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分子量
26 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SIKE1 (SIK1-interacting protein 1) is a protein that has garnered research interest due to its potential role in various biological processes, including cell signaling, apoptosis, and stress responses. Initially identified as an interaction partner of SIK1 (Salt-Inducible Kinase 1), SIKE1 is believed to modulate the activity of SIK1 and contribute to the regulation of cellular functions. Studies have shown that SIKE1 can influence pathways related to inflammation and metabolic regulation, highlighting its significance in diseases such as cancer and diabetes. The recombination of SIKE1 protein allows for the production of large quantities of this protein for functional assays and structural studies, providing insights into its mechanisms of action. Understanding SIKE1's interactions and functions could pave the way for novel therapeutic strategies, making it a valuable target for further research in molecular biology and drug development. The recombinant SIKE1 protein serves as a crucial tool for investigating its role in cellular processes and its potential implications in health and disease.
