Analytical Data
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Gene name
AAMP
- Application
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Alternative Names
AAMPAngio-associated migratory cell Protein
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q13685
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Expression Region
1-434aa
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AA Sequence
MESESESGAA ADTPPLETLS FHGDEEIIEV VELDPGPPDP DDLAQEMEDV DFEEEEEEEG NEEGWVLEPQ EGVVGSMEGP DDSEVTFALH SASVFCVSLD PKTNTLAVTG GEDDKAFVWR LSDGELLFEC AGHKDSVTCA GFSHDSTLVA TGDMSGLLKV WQVDTKEEVW SFEAGDLEWM EWHPRAPVLL AGTADGNTWM WKVPNGDCKT FQGPNCPATC GRVLPDGKRA VVGYEDGTIR IWDLKQGSPI HVLKGTEGHQ GPLTCVAANQ DGSLILTGSV DCQAKLVSAT TGKVVGVFRP ETVASQPSLG EGEESESNSV ESLGFCSVMP LAAVGYLDGT LAIYDLATQT LRHQCQHQSG IVQLLWEAGT AVVYTCSLDG IVRLWDARTG RLLTDYRGHT AEILDFALSK DASLVVTTSG DHKAKVFCVQ RPDR
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Molecular Weight
46.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
AAMP (Angiogenin-activating protein) has garnered significant attention in recent years due to its potential role in various biological processes, particularly in angiogenesis and tumor progression. The protein is primarily expressed in endothelial cells and has been implicated in vascular formation and maintenance. Research indicates that AAMP may enhance angiogenin activity, which is critical for promoting new blood vessel formation, a process vital for tumor growth and metastasis. The dysregulation of AAMP in certain cancers suggests it could serve as a biomarker for disease progression. Additionally, studies have shown that manipulating AAMP levels can influence endothelial cell behaviors such as migration and proliferation, highlighting its potential as a therapeutic target. Investigating AAMP's role extends beyond cancer, as it may also be involved in other pathological conditions related to vascular dysfunction. Understanding the molecular mechanisms underlying AAMP's functions is crucial for exploring innovative strategies in cancer therapy and regenerative medicine, making it a focal point of current research in the field of molecular biology and oncology.
