Analytical Data
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基因名
UCP3
- Application
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别名
UCP3;SLC25A9;Putative mitochondrial transporter UCP3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P55916
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表达区间
181-214aa
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氨基酸序列
GTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLT
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分子量
34.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
UCP3, or uncoupling protein 3, is a member of the mitochondrial transporter protein family that plays a vital role in regulating energy balance and thermogenesis in mammals. It is primarily expressed in skeletal muscle and brown adipose tissue, where it is thought to facilitate the dissipation of protons across the inner mitochondrial membrane, thereby reducing the production of ATP and generating heat instead. This function is particularly pertinent in the context of obesity and metabolic disorders, as UCP3 has been implicated in the mechanisms of energy expenditure and the regulation of fatty acid metabolism. Research into UCP3 recombinant protein has expanded our understanding of its physiological roles and potential therapeutic applications. By producing UCP3 as a recombinant protein, scientists can study its structure-function relationships, interactions with other mitochondrial proteins, and effects on mitochondrial bioenergetics in detail. Additionally, examining the effects of UCP3 overexpression or knockdown in various cellular models provides insights into its role in metabolic health and disease. This research is increasingly relevant in the face of rising global obesity rates and associated metabolic syndromes, highlighting UCP3's potential as a target for novel interventions aimed at enhancing energy expenditure and combating metabolic diseases. Overall, the study of UCP3 recombinant protein contributes significantly to our understanding of mitochondrial biology and its implications for human health.












