Analytical Data
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Gene name
NMUR2
- Application
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Alternative Names
NMUR2; NMU2R; TGR1; Neuromedin-U receptor 2; NMU-R2; G-protein coupled receptor FM-4; G-protein coupled receptor TGR-1
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9GZQ4
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Expression Region
1-415 aa
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AA Sequence
MSGMEKLQNASWIYQQKLEDPFQKHLNSTEEYLAFLCGPRRSHFFLPVSVVYVPIFVVGVIGNVLVCLVILQHQAMKTPTNYYLFSLAVSDLLVLLLGMPLEVYEMWRNYPFLFGPVGCYFKTALFETVCFASILSITTVSVERYVAILHPFRAKLQSTRRRALRILGIVWGFSVLFSLPNTSIHGIKFHYFPNGSLVPGSATFTVIKPMWIYNFIIQVTSFLFYLLPMTVISVLYYLMALRLKKDKSLEADEGNANIQRPCRKSVNKMLFVLVLVFAICWAPFHIDRLFFSFVEEWSESLAAVFNLVHVVSGVFFYLSSAVNPIIYNLLSRRFQAAFQNVISSFHKQWHSQHDPQLPPAQRNIFLTECHFVELTEDIGPQFPCQSSMHNSHLPTALSSEQMSRTNYQSFHFNKT
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Molecular Weight
71.39 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NMUR2, or Neuromedin U Receptor 2, is a G protein-coupled receptor (GPCR) that plays a critical role in various physiological functions, including energy homeostasis, stress response, and neuroendocrine regulation. As an important player in the neuromedin U signaling pathway, NMUR2 is implicated in several metabolic disorders, obesity, and mood regulation, making it a potential therapeutic target for drug development. The research surrounding NMUR2 recombinant proteins focuses on elucidating its structure, function, and signaling mechanisms to better understand its role in health and disease. The generation of high-quality NMUR2 recombinant proteins facilitates biochemical and pharmacological studies, allowing researchers to investigate receptor-ligand interactions, cell signaling pathways, and potential drug candidates. Additionally, understanding the receptor's structural characteristics can provide insights into the design of selective agonists or antagonists, thereby advancing the development of novel therapeutic strategies for metabolic and psychiatric disorders. Overall, the study of NMUR2 recombinant proteins is crucial for paving the way toward innovative treatments, highlighting the significance of GPCRs in biomedical research.
