Analytical Data
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基因名
ALDH3B1
- Application
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别名
ALDH3B1；ALDH7；Aldehyde dehydrogenase family 3 member B1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P43353
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表达区间
1-465aa
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氨基酸序列
MDPLGDTLRR LREAFHAGRT RPAEFRAAQL QGLGRFLQEN KQLLHDALAQ DLHKSAFESE VSEVAISQGE VTLALRNLRA WMKDERVPKN LATQLDSAFI RKEPFGLVLI IAPWNYPLNL TLVPLVGALA AGNCVVLKPS EISKNVEKIL AEVLPQYVDQ SCFAVVLGGP QETGQLLEHR FDYIFFTGSP RVGKIVMTAA AKHLTPVTLE LGGKNPCYVD DNCDPQTVAN RVAWFRYFNA GQTCVAPDYV LCSPEMQERL LPALQSTITR FYGDDPQSSP NLGRIINQKQ FQRLRALLGC GRVAIGGQSD ESDRYIAPTV LVDVQEMEPV MQEEIFGPIL PIVNVQSLDE AIEFINRREK PLALYAFSNS SQVVKRVLTQ TSSGGFCGND GFMHMTLASL PFGGVGASGM GRYHGKFSFD TFSHHRACLL RSPGMEKLNA LRYPPQSPRR LRMLLVAMEA QGCSC
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分子量
51.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ALDH3B1 (Aldehyde Dehydrogenase 3 Family Member B1) is a key enzyme involved in the detoxification of aldehydes and plays a significant role in cellular metabolism and oxidative stress response. Elevated levels of ALDH3B1 have been implicated in various pathological conditions, including cancer and neurodegenerative diseases, making it an important target for therapeutic research. The enzyme catalyzes the oxidation of aldehyde substrates to their corresponding carboxylic acids, thus preventing cellular damage and maintaining homeostasis. Recent studies have emphasized the importance of ALDH3B1 in determining cellular sensitivity to stressors, as well as its potential role in promoting cancer cell survival. As researchers continue to explore the structure-function relationships of ALDH3B1, the production and characterization of recombinant ALDH3B1 proteins have become essential for further investigations. These recombinant proteins allow for in-depth biochemical studies, helping to elucidate the enzyme's kinetics, substrate specificity, and inhibition mechanisms. Understanding the intricate workings of ALDH3B1 could lead to novel therapeutic strategies targeting its enzymatic activity, particularly in conditions where elevated aldehyde levels contribute to disease pathology. Consequently, recombinant ALDH3B1 is not only a valuable tool for basic research but also holds promise for the development of innovative treatments in medicine.
