Analytical Data
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Gene name
GPR39
- Application
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Alternative Names
GPR39；G-Protein coupled receptor 39
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O43194
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Expression Region
1-453aa
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AA Sequence
MASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSA TIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLT TSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPC QVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHE QPETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAFMCWNMMQVLM KSQKGSLAGGTRPPQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQ IRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQ FRRVFVQVLCCRLSLQHANHEKRLRVHAHSTTDSARFVQRPLLFASRRQS SARRTEKIFLSTFQSEAEPQSKSQSLSLESLEPNSGAKPANSAAENGFQE HEV
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Molecular Weight
78 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GPR39, a member of the G protein-coupled receptor (GPCR) family, has garnered significant interest due to its potential roles in various physiological and pathological processes. Originally identified as a zinc-sensing receptor, GPR39 is known to be involved in the regulation of metabolic pathways, neuronal activities, and inflammation. Studies have suggested that GPR39 may play a critical role in maintaining cellular homeostasis and has been implicated in conditions such as obesity, diabetes, and neurodegenerative diseases. The investigation of recombinant GPR39 proteins is vital for understanding the receptor's structure, function, and mechanisms of action. By producing and characterizing these proteins, researchers can explore ligand binding, signal transduction pathways, and the receptor's interactions with other cellular components. This research lays the groundwork for the development of novel therapeutic strategies targeting GPR39, highlighting its potential as a biomarker or drug target in metabolic and neurological disorders.
