Analytical Data
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Gene name
NAP1L3
- Application
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Alternative Names
NAP1L3; BNAP; Nucleosome assembly protein 1-like 3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q99457
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Expression Region
1-506 aa
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AA Sequence
MAEADFKMVS EPVAHGVAEE EMASSTSDSG EESDSSSSSS STSDSSSSSS TSGSSSGSGS SSSSSGSTSS RSRLYRKKRV PEPSRRARRA PLGTNFVDRL PQAVRNRVQA LRNIQDECDK VDTLFLKAIH DLERKYAELN KPLYDRRFQI INAEYEPTEE ECEWNSEDEE FSSDEEVQDN TPSEMPPLEG EEEENPKENP EVKAEEKEVP KEIPEVKDEE KEVPKEIPEV KAEEKADSKD CMEATPEVKE DPKEVPQVKA DDKEQPKATE AKARAAVRET HKRVPEERLQ DSVDLKRARK GKPKREDPKG IPDYWLIVLK NVDKLGPMIQ KYDEPILKFL SDVSLKFSKP GQPVSYTFEF HFLPNPYFRN EVLVKTYIIK AKPDHNDPFF SWGWEIEDCK GCKIDWRRGK DVTVTTTQSR TTATGEIEIQ PRVVPNASFF NFFSPPEIPM IGKLEPREDA ILDEDFEIGQ ILHDNVILKS IYYYTGEVNG TYYQFGKHYG NKKYRK
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Molecular Weight
57.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NAP1L3, a member of the nucleosome assembly protein (NAP) family, plays a crucial role in chromatin dynamics and gene regulation. Research has shown that NAP1L3 is involved in the assembly of nucleosomes and is essential for the proper organization of chromatin, which in turn influences gene expression and cellular function. Dysregulation of NAP1L3 has been implicated in various diseases, including cancer and developmental disorders, highlighting its potential as a therapeutic target. The recombination of NAP1L3 protein allows for detailed structural and functional studies, aiding in the understanding of its mechanisms within the cell. Further investigations into NAP1L3's interactions with histones and other chromatin-associated proteins could provide insights into its role in epigenetic regulation and cellular responses to external stimuli. Additionally, recombinant NAP1L3 can serve as a valuable tool for studying nucleosome assembly processes and the development of novel therapeutic strategies targeting chromatin-related diseases. Overall, comprehensive studies of NAP1L3 and its recombinant forms are crucial for elucidating its biological significance and therapeutic potential in cancer and other disorders.
