Analytical Data
-
Gene name
NAP1L2
- Application
-
Alternative Names
NAP1L2; BPX; Nucleosome assembly protein 1-like 2; Brain-specific protein; X-linked
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9ULW6
-
Expression Region
1-460 aa
-
AA Sequence
MAESENRKEL SESSQEEAGN QIMVEGLGEH LERGEDAAAG LGDDGKCGEE AAAGLGEEGE NGEDTAAGSG EDGKKGGDTD EDSEADRPKG LIGYVLDTDF VESLPVKVKY RVLALKKLQT RAANLESKFL REFHDIERKF AEMYQPLLEK RRQIINAIYE PTEEECEYKS DSEDCDDEEM CHEEMYGNEE GMVHEYVDED DGYEDYYYDY AVEEEEEEEE EDDIEATGEE NKEEEDPKGI PDFWLTVLKN VDTLTPLIKK YDEPILKLLT DIKVKLSDPG EPLSFTLEFH FKPNEYFKNE LLTKTYVLKS KLAYYDPHPY RGTAIEYSTG CEIDWNEGKN VTLKTIKKKQ KHRIWGTIRT VTEDFPKDSF FNFFSPHGIT SNGRDGNDDF LLGHNLRTYI IPRSVLFFSG DALESQQEGV VREVNDAIYD KIIYDNWMAA IEEVKACCKN LEALVEDIDR
-
Molecular Weight
52.5 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NAP1L2, a member of the nucleosome assembly protein (NAP) family, plays a critical role in the processes of chromatin assembly and DNA packaging within the nucleus. It is known to facilitate the nucleosome formation by binding to histones and enhancing their assembly into nucleosome structures. Research into NAP1L2 has gained significance due to its potential implications in chromatin remodeling and gene regulation. Abnormalities in chromatin dynamics, often linked to NAP proteins, have been associated with various cancers and developmental disorders. Moreover, NAP1L2 is involved in cellular responses to DNA damage, further highlighting its importance in maintaining genomic integrity. Advances in recombinant protein technology have enabled the production of NAP1L2, allowing for in-depth studies of its structure and function, and how it interacts with other chromatin-associated proteins. By elucidating the mechanisms by which NAP1L2 operates, researchers aim to uncover its precise role in epigenetic regulation and its potential involvement in disease mechanisms. Thus, the study of NAP1L2 not only enhances our understanding of chromatin biology but also opens up new avenues for therapeutic interventions targeting chromatin dynamics in various pathologies.
