Analytical Data
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基因名
NAB1
- Application
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别名
EGR 1 binding protein 1; EGR-1-binding protein 1; EGR1 binding protein 1; NAB1; NAB1_HUMAN; NGFI A binding protein 1 (EGR1 binding protein 1); NGFI A binding protein 1; NGFI-A-binding protein 1; Transcriptional regulatory protein p54
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q13506
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表达区间
1-486 aa
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氨基酸序列
MAAALPRTLG ELQLYRILQK ANLLSYFDAF IQQGGDDVQQ LCEAGEEEFL EIMALVGMAS KPLHVRRLQK ALRDWVTNPG LFNQPLTSLP VSSIPIYKLP EGSPTWLGIS CSSYERSSNA REPHLKIPKC AATTCVQSLG QGKSDVVGSL ALQSVGESRL WQGHHATESE HSLSPADLGS PASPKESSEA LDAAAALSVA ECVERMAPTL PKSDLNEVKE LLKTNKKLAK MIGHIFEMND DDPHKEEEIR KYSAIYGRFD SKRKDGKHLT LHELTVNEAA AQLCVKDNAL LTRRDELFAL ARQISREVTY KYTYRTTKSK CGERDELSPK RIKVEDGFPD FQDSVQTLFQ QARAKSEELA ALSSQQPEKV MAKQMEFLCN QAGYERLQHA ERRLSAGLYR QSSEEHSPNG LTSDNSDGQG ERPLNLRMPN LQNRQPHHFV VDGELSRLYP SEAKSHSSES LGILKDYPHS AFTLEKKVIK TEPEDS
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分子量
54.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NAB1 (Nuclear Anomaly-Binding protein 1) is a crucial protein involved in various cellular processes, particularly in regulating gene expression and mRNA stability. Its significance has been underscored by findings that suggest NAB1 plays a role in cellular response to stress and inflammation, which are critical in both normal physiological functions and pathological conditions, such as cancer and neurodegenerative diseases. The interest in NAB1 restructured protein research lies in its potential as a therapeutic target; understanding its structural and functional dynamics can illuminate its role in disease mechanisms. Furthermore, NAB1's interactions with other proteins and its influence on transcriptional regulation make it a focal point in the study of gene regulatory networks. Researchers aim to elucidate its structure through recombinant DNA technology, allowing for the production of purified NAB1 protein for functional assays and structural studies. This approach not only enhances knowledge about NAB1's biological roles but also facilitates the discovery of small molecules or biologics that could modulate its activity, potentially leading to novel therapeutic strategies. The exploration of NAB1 restructured protein continues to be a promising avenue in biomedicine, providing insights into gene regulation and contributing to the development of innovative treatments for various diseases.












