Analytical Data
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Gene name
RAB8B
- Application
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Alternative Names
RAB8B;Ras-related Protein Rab-8B
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q92930
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Expression Region
1-204aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMAKTYDY LFKLLLIGDS GVGKTCLLFR FSEDAFNTTF ISTIGIDFKI RTIELDGKKI KLQIWDTAGQ ERFRTITTAY YRGAMGIMLV YDITNEKSFD NIKNWIRNIE EHASSDVERM ILGNKCDMND KRQVSKERGE KLAIDYGIKF LETSAKSSAN VEEAFFTLAR DIMTKLNRKM NDSNSAGAGG PVKITENRSK KTSFFRC
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Molecular Weight
26 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RAB8B is a member of the RAB family of small GTPases, which are crucial regulators of intracellular membrane trafficking and signal transduction. Within the context of cellular biology, RAB8B has garnered attention for its role in the regulation of vesicle transport processes, particularly in the context of the late steps of the endosomal and exocytic pathways. Understanding the function of RAB8B is essential due to its involvement in various cellular functions, including cell proliferation, differentiation, and polarity, and its potential links to disease states such as cancer and neurodegeneration. Studies have shown that RAB8B is implicated in the proper localization of proteins to the plasma membrane and is vital for the secretion of multiple signaling molecules. The recombinant expression of RAB8B in vitro provides researchers with valuable tools to investigate its biochemical properties, interaction with effector proteins, and overall contribution to cellular Homeostasis. Furthermore, characterizing RAB8B through recombinant protein techniques aids in deciphering its mechanisms of action and exploring its potential as a therapeutic target in pathologies linked to dysfunctional cellular trafficking. Consequently, the study of RAB8B recombinant protein is not only important for elucidating the fundamental aspects of intracellular transport dynamics but also for identifying novel strategies for disease intervention.
