Analytical Data
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Gene name
MYBPH
- Application
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Alternative Names
bHLHe38; H protein ; H-protein; l-myc protein; l-myc-1 proto-oncogene; LMYC; MyBP H; MyBP-H; Mybph; MYBPH_HUMAN; myc-related gene from lung cancer; MYCL; Myosin binding protein H; Myosin binding protein. 86-KD; Myosin-binding protein H; Oncogene lmyc; V-myc avian myelocytomatosis viral oncogene homolog 1. lung carcinoma derived
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q13203
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Expression Region
1-477 aa
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AA Sequence
MMEKNTSEGP ACSPEETASE SAKVPTAEPP GEVAVSESTR EEQVPKPQAP APQAPTASTA TKPAPPSEDV PSAPLLLTLD DVSSSSVTVS WEPPERLGRL GLQGYVLELC REGASEWVPV SARPMMVTQQ TVRNLALGDK FLLRVSAVSS AGAGPPAMLD QPIHIRENIE APKIRVPRHL RQTYIRQVGE TVNLQIPFQG KPKPQATWTH NGHALDSQRV SMRTGDQDSI LFIRSAQRSD SGRYELTVRV EDLEAKAVID ILVIEKPGPP SSIRLLDVWG CNAALQWTPP QDTGNTELLG YMVQKADKKT GQWFTVLERY HPTTCTISDL IIGNSYSFRV FSENLCGLST SATVTKELAH IQKADIAAKP KGFIERDFSE APSFTQPLAD HTSTPGYSTQ LFCSVRASPK PKIIWMKNKM EIQGNPKYRA LSEQGVCTLE IRKPSPFDSG VYTCKAINVL GEASVDCRLE VKASAAH
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Molecular Weight
52.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MYBPH (Myosin Binding Protein H) is a member of the MYB gene family, primarily expressed in cardiac and skeletal muscles, where it plays a critical role in muscle contraction and structural integrity. Research into MYBPH has gained traction due to its potential involvement in various cardiac diseases and its regulatory functions in muscle physiology. The protein is believed to interact with myosin and other sarcomeric proteins, thereby influencing muscle contraction dynamics and overall muscle function. Alterations or mutations in the MYBPH gene have been linked to genetic cardiomyopathies, making it a significant target for understanding the molecular mechanisms underlying heart disease. Additionally, studying the recombinant MYBPH protein aids in elucidating its functional properties, interactions, and potential therapeutic applications. The production of MYBPH as a recombinant protein allows researchers to explore its biophysical characteristics, investigate binding affinities with myosin, and identify post-translational modifications that may impact its activity. Overall, MYBPH remains a critical focus of research aimed at developing strategies for treating muscle-related disorders and enhancing our understanding of muscle biology at the molecular level.
