Analytical Data
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基因名
RAB39B
- Application
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别名
RAB39B;Ras-related Protein Rab-39B
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96DA2
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表达区间
1-213aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMEAIWLY QFRLIVIGDS TVGKSCLIRR FTEGRFAQVS DPTVGVDFFS RLVEIEPGKR IKLQIWDTAG QERFRSITRA YYRNSVGGLL LFDITNRRSF QNVHEWLEET KVHVQPYQIV FVLVGHKCDL DTQRQVTRHE AEKLAAAYGM KYIETSARDA INVEKAFTDL TRDIYELVKR GEITIQEGWE GVKSGFVPNV VHSSEEVVKS ERRCLC
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分子量
27 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RAB39B is a member of the RAB family of small GTPases, which are crucial in regulating intracellular trafficking processes, including vesicle transport and membrane dynamics. Mutations in the RAB39B gene have been linked to X-linked intellectual disability and autism spectrum disorders, highlighting its significance in neurodevelopment. Research has increasingly focused on RAB39B due to its role in neuronal function and its potential involvement in synaptic plasticity. The development of recombinant RAB39B protein allows for advanced studies into its biological functions and interactions with other cellular components. Characterizing this protein can provide insights into its mechanisms of action and elucidate how dysregulation may contribute to neurodevelopmental disorders. Furthermore, understanding the structural and functional properties of RAB39B can pave the way for potential therapeutic strategies targeting its pathways, offering hope for interventions in conditions associated with its dysfunction. As such, RAB39B serves as an important model for elucidating the molecular underpinnings of neurodevelopment and related diseases.












