Analytical Data
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基因名
RAB34
- Application
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别名
RAB34;RAB39;RAH;Ras-related Protein Rab-34
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BZG1
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表达区间
1-259aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMNILAPVRRDRVLAELPQCLRKEAALHGHK DFHPRVTCACQEHRTGTVGFKISKVIVVGDLSVGKTCLINRFCKDTFDKN YKATIGVDFEMERFEVLGIPFSLQLWDTAGQERFKCIASTYYRGAQAIII VFNLNDVASLEHTKQWLADALKENDPSSVLLFLVGSKKDLSTPAQYALME KDALQVAQEMKAEYWAVSSLTGENVREFFFRVAALTFEANVLAELEKSGA RRIGDVVRINSDDSNLYLTASKKKPTCCP
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分子量
31 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RAB34 is a member of the RAS superfamily of small GTPases, which play crucial roles in intracellular trafficking, membrane transport, and cellular signaling. Recent studies have highlighted the involvement of RAB34 in various cellular processes, including endocytosis, exocytosis, and organelle dynamics, making it a significant focus in cell biology and molecular research. Understanding the functional mechanisms of RAB34 is essential for unraveling its contributions to normal cellular physiology and potential implications in disease states, such as cancer and neurodegenerative disorders. Recombinant RAB34 proteins have been produced to elucidate its structural features and functional roles, enabling researchers to explore its interaction with effector proteins and its regulation by guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs). Investigating RAB34 through recombinant techniques also facilitates high-throughput screening of potential therapeutic agents that may target RAB34-related pathways. Overall, the study of recombinant RAB34 proteins is pivotal for advancing our understanding of this GTPase's role in cellular homeostasis and its potential as a biomarker or therapeutic target in various diseases.
