Analytical Data
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基因名
RAB1B
- Application
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别名
RAB1B;Ras-related Protein Rab-1B
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H0U4
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表达区间
1-199aa
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氨基酸序列
MNPEYDYLFK LLLIGDSGVG KSCLLLRFAD DTYTESYIST IGVDFKIRTI ELDGKTIKLQ IWDTAGQERF RTITSSYYRG AHGIIVVYDV TDQESYANVK QWLQEIDRYA SENVNKLLVG NKSDLTTKKV VDNTTAKEFA DSLGIPFLET SAKNATNVEQ AFMTMAAEIK KRMGPGAASG GERPNLKIDS TPVKPAGGG
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分子量
50 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RAB1B, a member of the Ras-related proteins superfamily, plays a crucial role in intracellular transport and membrane trafficking. It is primarily localized to the endoplasmic reticulum (ER) and is involved in the regulation of vesicle formation and transport between the ER and the Golgi apparatus. Research has shown that RAB1B is essential for proper protein secretion and plays a significant role in various cellular processes, including autophagy, cell signaling, and maintaining cellular homeostasis. Dysregulation of RAB1B has been implicated in several diseases, including cancer, neurodegenerative disorders, and viral infections, highlighting its potential as a therapeutic target. Given its importance in cellular function, there is growing interest in studying RAB1B through recombinant protein techniques. Producing RAB1B as a recombinant protein allows for in-depth analysis of its structure, function, and interaction with other cellular components. Such studies can provide insights into the molecular mechanisms governing vesicle trafficking and identify novel strategies for intervention in diseases associated with RAB1B dysfunction. Understanding RAB1B's role at the molecular level could pave the way for the development of targeted therapies aiming to restore normal cellular transport processes in pathological conditions. Overall, research on RAB1B recombinant protein is fundamental for elucidating its biological functions and for exploring its potential as a biomarker or a target for novel therapeutic interventions.
