Analytical Data
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Gene name
RAB1B
- Application
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Alternative Names
RAB1B;Ras-related Protein Rab-1B
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H0U4
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Expression Region
1-199aa
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AA Sequence
MNPEYDYLFK LLLIGDSGVG KSCLLLRFAD DTYTESYIST IGVDFKIRTI ELDGKTIKLQ IWDTAGQERF RTITSSYYRG AHGIIVVYDV TDQESYANVK QWLQEIDRYA SENVNKLLVG NKSDLTTKKV VDNTTAKEFA DSLGIPFLET SAKNATNVEQ AFMTMAAEIK KRMGPGAASG GERPNLKIDS TPVKPAGGG
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Molecular Weight
50 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RAB1B, a member of the Ras-related proteins superfamily, plays a crucial role in intracellular transport and membrane trafficking. It is primarily localized to the endoplasmic reticulum (ER) and is involved in the regulation of vesicle formation and transport between the ER and the Golgi apparatus. Research has shown that RAB1B is essential for proper protein secretion and plays a significant role in various cellular processes, including autophagy, cell signaling, and maintaining cellular homeostasis. Dysregulation of RAB1B has been implicated in several diseases, including cancer, neurodegenerative disorders, and viral infections, highlighting its potential as a therapeutic target. Given its importance in cellular function, there is growing interest in studying RAB1B through recombinant protein techniques. Producing RAB1B as a recombinant protein allows for in-depth analysis of its structure, function, and interaction with other cellular components. Such studies can provide insights into the molecular mechanisms governing vesicle trafficking and identify novel strategies for intervention in diseases associated with RAB1B dysfunction. Understanding RAB1B's role at the molecular level could pave the way for the development of targeted therapies aiming to restore normal cellular transport processes in pathological conditions. Overall, research on RAB1B recombinant protein is fundamental for elucidating its biological functions and for exploring its potential as a biomarker or a target for novel therapeutic interventions.
