Analytical Data
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基因名
MTA3
- Application
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别名
1110002J22Rik; fj99h01; KIAA1266; Metastasis associated 1 family. member 3; Metastasis associated 3; Metastasis associated family. member 3; Metastasis associated gene 3; Metastasis associated gene family. member 3; Metastasis associated protein MTA3; Metastasis-associated protein MTA3; MGC56396; MGC77410; mKIAA1266; mta1; Mta3; MTA3 metastasis associated 1 family. member 3; Mta3 metastasis associated 3; MTA3_HUMAN; wu:fj99h01; zgc:56396
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BTC8
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表达区间
1-594 aa
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氨基酸序列
MAANMYRVGD YVYFENSSSN PYLIRRIEEL NKTASGNVEA KVVCFYRRRD ISNTLIMLAD KHAKEIEEES ETTVEADLTD KQKHQLKHRE LFLSRQYESL PATHIRGKCS VALLNETESV LSYLDKEDTF FYSLVYDPSL KTLLADKGEI RVGPRYQADI PEMLLEGESD EREQSKLEVK VWDPNSPLTD RQIDQFLVVA RAVGTFARAL DCSSSVRQPS LHMSAAAASR DITLFHAMDT LYRHSYDLSS AISVLVPLGG PVLCRDEMEE WSASEASLFE EALEKYGKDF NDIRQDFLPW KSLTSIIEYY YMWKTTDRYV QQKRLKAAEA ESKLKQVYIP TYSKPNPNQI STSNGKPGAV NGAVGTTFQP QNPLLGRACE SCYATQSHQW YSWGPPNMQC RLCAICWLYW KKYGGLKMPT QSEEEKLSPS PTTEDPRVRS HVSRQAMQGM PVRNTGSPKS AVKTRQAFFL HTTYFTKFAR QVCKNTLRLR QAARRPFVAI NYAAIRAEYA DRHAELSGSP LKSKSTRKPL ACIIGYLEIH PAKKPNVIRS TPSLQTPTTK RMLTTPNHTS LSILGKRNYS HHNGLDELTC CVSD
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分子量
67.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MTA3 (Metastasis-associated protein 3) is a member of the MYB-related protein family that has been implicated in various biological processes, including cell proliferation, differentiation, and cancer metastasis. Its role in the regulation of gene expression and its interaction with chromatin-modifying complexes make it an important player in cancer biology. Research has indicated that MTA3 functions as a transcriptional repressor, modulating the expression of target genes involved in tumor progression and metastasis. Studies have shown that altered MTA3 expression levels correlate with tumor progression and poor prognosis in several cancers, suggesting its potential as a biomarker for cancer diagnosis and treatment. Additionally, investigations into the molecular mechanisms of MTA3 interactions with other proteins and regulatory pathways can provide insights into its role in tumorigenesis. The development of MTA3 recombinant proteins facilitates detailed studies on its structure-function relationships and interactions, paving the way for more targeted therapeutic strategies in cancer management. Overall, the study of MTA3 represents an important aspect of understanding the complexities of cancer biology and identifying new avenues for intervention.
