Analytical Data
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Gene name
MT1K
- Application
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Alternative Names
MT1M; MT1K; Metallothionein-1M; MT-1M; Metallothionein-IM; MT-IM
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8N339
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Expression Region
1-61 aa
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AA Sequence
MDPNCSCTTG VSCACTGSCT CKECKCTSCK KSCCSCCPVG CAKCAHGCVC KGTLENCSCC A
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Molecular Weight
6.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The MT1K protein, a member of the metallothionein family, plays a crucial role in heavy metal ion binding and detoxification, as well as in cellular processes like proliferation, differentiation, and apoptosis. Research into MT1K has gained traction due to its potential implications in various diseases, including cancer, neurodegenerative disorders, and metabolic syndromes. The protein's capacity to sequester toxic metals, such as cadmium and lead, positions it as a significant player in maintaining cellular homeostasis and mitigating oxidative stress. Recent studies have focused on the expression, structure, and functional mechanisms of MT1K, revealing insights into how this protein interacts with metal ions at the molecular level. Moreover, the recombinant production of MT1K has enabled detailed investigations into its properties and applications in biotechnology and medicine, including drug development and biomonitoring of metal exposure. Understanding the biochemical pathways and regulatory networks involving MT1K may yield novel therapeutic strategies, enhancing our ability to combat metal toxicity and related diseases. As such, ongoing research continues to explore the multifaceted roles of MT1K, positioning it as a pivotal element in the study of metallobiology and its therapeutic potential.
