Analytical Data
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Gene name
SF1
- Application
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Alternative Names
SF1；SF4；SURP and G-patch domain-containing Protein 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q13285
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Expression Region
1-461aa
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AA Sequence
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
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Molecular Weight
59.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The SF1 (Steroidogenic Factor 1) protein is a crucial transcription factor belonging to the nuclear receptor family, which plays a vital role in the regulation of various physiological processes, including adrenal steroidogenesis, reproductive system development, and metabolism. Its expression is particularly prominent in endocrine tissues such as the adrenal glands and gonads. Research on SF1 has gained momentum due to its involvement in multiple signaling pathways and its potential implications in various endocrine disorders, including adrenal insufficiency and infertility. The study of SF1 recombinant protein has emerged as a significant area of interest, as it allows for detailed investigations into its structural properties, functional roles, and interactions with other molecular partners. Advances in recombinant DNA technology have facilitated the production of SF1 proteins for characterizing their biochemical and biophysical properties. Furthermore, understanding SF1's mechanisms and regulation can provide insights into the pathophysiology of related diseases and aid in the development of novel therapeutic strategies. Consequently, the recombinant expression and purification of SF1 not only enhance our understanding of its fundamental biological roles but also position it as a potential target for drug discovery in endocrine-related conditions.
