Analytical Data
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Gene name
MSL3L1
- Application
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Alternative Names
MSL3; AU018931; DKFZp586J1822; Drosophila MSL3 like 1; Male specific lethal 3 (Drosophila) like 1; Male specific lethal 3 homolog (Drosophila); Male specific lethal 3 homolog 1 (Drosophila); Male specific lethal 3 homolog 1; Male specific lethal 3 homolog; Male specific lethal 3 like 1 (Drosophila); Male specific lethal 3 like 1; Male specific lethal 3 protein like 1; Male-specific lethal 3 homolog; Male-specific lethal-3 homolog 1; Male-specific lethal-3 protein-like 1; MS3L1_HUMAN; MSL3; MSL3 like 1; MSL3-like 1; Msl31; MSL3L1; OTTHUMP00000022911 ; OTTHUMP00000022912
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8N5Y2
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Expression Region
1-521 aa
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AA Sequence
MSASEGMKFK FHSGEKVLCF EPDPTKARVL YDAKIVDVIV GKDEKGRKIP EYLIHFNGWN RSWDRWAAED HVLRDTDENR RLQRKLARKA VARLRSTGRK KKRCRLPGVD SVLKGLPTEE KDENDENSLS SSSDCSENKD EEISEESDIE EKTEVKEEPE LQTRREMEER TITIEIPEVL KKQLEDDCYY INRRKRLVKL PCQTNIITIL ESYVKHFAIN AAFSANERPR HHHVMPHANM NVHYIPAEKN VDLCKEMVDG LRITFDYTLP LVLLYPYEQA QYKKVTSSKF FLPIKESATS TNRSQEELSP SPPLLNPSTP QSTESQPTTG EPATPKRRKA EPEALQSLRR STRHSANCDR LSESSASPQP KRRQQDTSAS MPKLFLHLEK KTPVHSRSSS PIPLTPSKEG SAVFAGFEGR RTNEINEVLS WKLVPDNYPP GDQPPPPSYI YGAQHLLRLF VKLPEILGKM SFSEKNLKAL LKHFDLFLRF LAEYHDDFFP ESAYVAACEA HYSTKNPRAI Y
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Molecular Weight
59.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MSL3L1 (Male-specific lethal 3-like protein 1) is a crucial member of the MSL (Male-Specific Lethal) family of proteins, primarily involved in the dosage compensation mechanism in Drosophila, which ensures that males and females express X-linked genes at equivalent levels. This protein plays a significant role in the regulation of transcription and has been implicated in various biological processes, including development, gene expression, and chromatin remodeling. Recent studies have highlighted the importance of MSL3L1 in modulating epigenetic modifications and influencing gene activity through its interactions with other chromatin-associated factors. Given its potential involvement in human disorders, such as developmental and reproductive abnormalities, understanding the structure and function of MSL3L1 is essential. Research on recombinant MSL3L1 proteins has opened new avenues for investigating its biological functions and mechanisms, providing insights that could lead to therapeutic interventions. The characterization of MSL3L1 recombinant proteins allows for the exploration of its binding properties and interactions at the molecular level, paving the way for future studies aimed at elucidating its role in health and disease.
