Analytical Data
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基因名
hcp1
- Application
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别名
hcp1;G21;HCP1;PCFT;Proton-coupled folate transporter
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9I747
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表达区间
24.9 kDa
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氨基酸序列
MAVDMFIKIGDVKGESKDKTHAEEIDVLAWSWGMSQSGSMHMGGGGGAGKVNVQDLSFTKYIDKSTPNLMMACSSGKHYPQAKLTIRKAGGENQVEYLIITLKEVLVSSVSTGGSGGEDRLTENVTLNFAQVQVDYQPQKADGAKDGGPVKYGWNIRQNVQA
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分子量
24.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HCP1 (Human Copper Transporter 1) is a vital protein involved in the regulation of copper homeostasis in the body. Research on HCP1 has gained prominence due to the critical role copper plays in various biological processes, including enzymatic reactions, oxidative stress response, and mitochondrial function. Dysregulation of copper transport can lead to pathological conditions such as Wilson's disease and Menkes disease, both of which are associated with severe neurological and developmental issues. Understanding the molecular structure and function of HCP1 is essential for elucidating its role in copper metabolism and its implications in disease states. Recent advancements in recombinant protein technology have enabled the production of HCP1 in significant quantities, facilitating in-depth studies of its biochemical properties and interactions. The ability to characterize HCP1 using techniques such as X-ray crystallography and NMR spectroscopy will provide insights into its mechanism of action and potential as a therapeutic target. Additionally, the study of HCP1 may reveal new avenues for drug development aimed at correcting copper transport dysregulation, thus contributing to the treatment of related disorders. As research progresses, HCP1 is emerging as an important player in the field of molecular biology and medicine, underscoring the necessity for further exploration of its functions and therapeutic potential.












