Analytical Data
-
基因名
MRPL46
- Application
-
别名
39S ribosomal protein L46; 39S ribosomal protein L46 mitochondrial; C15orf4; L46mt; LIECG 2; LIECG2; MGC22762; mitochondrial; Mitochondrial ribosomal protein L46; MRP L46; MRP-L46; MRPL 46; Mrpl46; P2ECSL; RM46_HUMAN
-
种属
Human
-
表达系统
E. coli
-
标签
GST-tag at N-terminal
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9H2W6
-
表达区间
1-279 aa
-
氨基酸序列
MAAPVRRTLLGVAGGWRRFERLWAGSLSSRSLALAAAPSSNGSPWRLLGALCLQRPPVVSKPLTPLQEEMASLLQQIEIERSLYSDHELRALDENQRLAKKKADLHDEEDEQDILLAQDLEDMWEQKFLQFKLGARITEADEKNDRTSLNRKLDRNLVLLVREKFGDQDVWILPQAEWQPGETLRGTAERTLATLSENNMEAKFLGNAPCGHYTFKFPQAMRTESNLGAKVFFFKALLLTGDFSQAGNKGHHVWVTKDELGDYLKPKYLAQVRRFVSDL
-
分子量
58.1 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MRPL46, a mitochondrial ribosomal protein, plays a vital role in the synthesis of mitochondrial proteins, which are essential for oxidative phosphorylation and cellular respiration. As a member of the mitochondrial large ribosomal subunit, MRPL46 is involved in translating mitochondrial mRNA, contributing to the proper functioning of the mitochondrial machinery. Recent studies have highlighted the significance of mitochondrial ribosomes in cellular metabolism and their implications in various diseases, including mitochondrial disorders and age-related pathologies. Given the emerging evidence linking MRPL46 and mitochondrial function to important cellular processes such as apoptosis and stress responses, understanding its structure and function could provide insights into the molecular mechanisms underlying these conditions. The recombinant expression of MRPL46 in model organisms and cell lines offers a valuable approach to investigate its biochemical properties, interactions with other mitochondrial components, and potential role in disease mechanisms. Overall, characterizing MRPL46 as a recombinant protein not only furthers our understanding of mitochondrial biology but also opens avenues for potential therapeutic interventions targeting mitochondrial dysfunction.
