Analytical Data
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基因名
MRPL47
- Application
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别名
39S ribosomal protein L47 mitochondrial; 39S ribosomal protein L47. mitochondrial; CGI 204; L47mt; MGC45403; Mitochondrial ribosomal protein L47; MRP L47; MRP-L47; MRPL 47; MRPL47; Nasopharyngeal carcinoma metastasis related 1; Nasopharyngeal carcinoma metastasis related protein 1; Nasopharyngeal carcinoma metastasis-related protein 1; NCM1; RM47_HUMAN
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9HD33
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表达区间
1-140 aa
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氨基酸序列
MLLTLEQEAKRQRLPMPSPERLDKVVDSMDALDKVVQEREDALRLLQTGQERARPGAWRRDIFGRIIWHKFKQWVIPWHLNKRYNRKRFFALPYVDHFLRLEREKRARIKARKENLERKKAKILLKKFPHLAEAQKSSLV
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分子量
43.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MRPL47, a mitochondrial ribosomal protein, plays a crucial role in protein synthesis within mitochondria, which are essential for cellular energy production and metabolism. Recent studies have highlighted the importance of mitochondrial function in various biological processes, including apoptosis, oxidative stress response, and cellular metabolism. Given that mitochondrial dysfunction is implicated in multiple diseases, including neurodegenerative disorders, metabolic syndromes, and cancer, understanding the role of MRPL47 is increasingly vital. Research has shown that MRPL47 may influence mitochondrial translation and ribosome assembly, thus impacting mitochondrial gene expression and the overall functionality of the organelle. Additionally, mutations or dysregulation of MRPL47 have been linked to mitochondrial diseases, providing further motivation to study this protein in detail. Characterizing the structure and function of MRPL47 can offer insights into novel therapeutic approaches for conditions associated with mitochondrial dysfunction. Furthermore, by exploring its interactions with other mitochondrial components, researchers aim to elucidate the mechanisms by which MRPL47 contributes to mitochondrial health and disease, paving the way for advancements in targeted therapies and potential biomarkers for mitochondrial-related pathologies.
