Cat: PA2000-9467

Recombinant Human MRPL41 Protein,His

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Analytical Data

  • Gene name

    MRPL41

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    39S ribosomal protein L27 homolog; 39S ribosomal protein L41; 39S ribosomal protein L41 mitochondrial; Bcl-2-interacting mitochondrial ribosomal protein L41; BMRP; Cell proliferation-inducing gene 3 protein; L41mt; mitochondrial; Mitochondrial ribosomal protein L41; MRP L27; MRP-L27 homolog; MRP-L41; MRPL27; mRpL41; PIG3; Proliferation inducing gene 3; RM41_HUMAN; RPML27

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8IXM3

  • Expression Region

    14-137 aa

  • AA Sequence

    GADRMSK WTSKRGPRSF RGRKGRGAKG IGFLTSGWRF VQIKEMVPEF VVPDLTGFKL KPYVSYLAPE SEETPLTAAQ LFSEAVAPAI EKDFKDGTFD PDNLEKYGFE PTQEGKLFQL YPRNFLR

  • Molecular Weight

    15.3 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

MRPL41, or Mitochondrial Ribosomal Protein L41, is a crucial component of the mitochondrial ribosome, which plays a vital role in protein synthesis within mitochondria. Research into MRPL41 has gained prominence due to its significant involvement in mitochondrial function and the implications it has for cellular energy production. Mutations or dysregulation of MRPL41 have been linked to various mitochondrial diseases and disorders, which can lead to severe metabolic dysfunctions and contribute to aging-related pathologies. Additionally, studies have shown that MRPL41 may have a role in the ribosome's structural integrity and its interaction with mitochondrial transfer RNA (tRNA). The exploration of MRPL41 recombinant protein is essential for understanding its biological activities and molecular mechanisms. By producing and characterizing this protein, researchers aim to uncover its functional roles, interactions, and potential as a therapeutic target. Overall, the study of MRPL41 and its recombinant protein is critical for advancing knowledge in mitochondrial biology, disease mechanisms, and developing novel therapeutic strategies to tackle mitochondrial-related disorders.

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