Analytical Data
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Gene name
MRPL23
- Application
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Alternative Names
L23MRP; 39S ribosomal protein L23; 39S ribosomal protein L23; mitochondrial; L23 mitochondrial-related protein; L23mt; mitochondrial; Mitochondrial ribosomal protein L23; MRP-L23; MRPL23; Ribosomal protein L23-like; Ribosomal protein related to L23 (mitochondrial); RM23_HUMAN; RPL23; RPL23L
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q16540
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Expression Region
1-153 aa
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AA Sequence
MARNVVYPLY RLGGPQLRVF RTNFFIQLVR PGVAQPEDTV QFRIPMEMTR VDLRNYLEGI YNVPVAAVRT RVQHGSNKRR DHRNVRIKKP DYKVAYVQLA HGQTFTFPDL FPEKDESPEG SAADDLYSML EEERQQRQSS DPRRGGVPSW FGL
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Molecular Weight
17.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MRPL23, or Mitochondrial Ribosomal Protein L23, is a crucial component of the mitochondrial ribosome, playing a significant role in mitochondrial protein synthesis. This protein is encoded by a nuclear gene and is imported into mitochondria, where it contributes to the assembly and function of the mitochondrial ribosomal complex. Research on MRPL23 has gained interest due to its potential implications in various disorders, particularly those related to mitochondrial dysfunction. Mitochondrial diseases, which can lead to a range of symptoms including muscle weakness, neurological issues, and metabolic disturbances, often stem from defects in mitochondrial protein synthesis. Moreover, recent studies have suggested that abnormalities in MRPL23 may be linked to certain types of cancer and aging processes. Understanding the structure, function, and regulatory mechanisms of MRPL23 can provide insights into mitochondrial biology and the pathology of related diseases. Investigating MRPL23 recombinant protein allows researchers to explore its interactions with other mitochondrial components and to assess its role in translational control and mitochondrial dynamics. This research holds promise not only for advancing our basic understanding of mitochondrial function but also for the development of therapeutic strategies aimed at ameliorating mitochondrial-related conditions.
