Analytical Data
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基因名
KRT32
- Application
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别名
KRT32；HHA2；HKA2；KRTHA2；Keratin. type I cuticular Ha2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q14532
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表达区间
1-448aa
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氨基酸序列
MTSSCCVTNNLQASLKSCPRPASVCSSGVNCRPELCLGYVCQPMACLPSVCLPTTFRPASCLSKTYLSSSCQAASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKLPCNPCSTPSCTTCVPSPCVPRTVCVPRTVGMPCSPCPQGRY
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分子量
57.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KRT32, also known as keratin 32, is a type I cytokeratin that plays a crucial role in the structure and function of epithelial tissues. As a member of the keratin family, KRT32 is primarily expressed in hair follicles and certain stratified epithelial tissues, contributing to their mechanical resilience and integrity. Research into KRT32 has gained importance due to its potential implications in various skin disorders and hair follicle pathologies. Abnormal expression or mutations in keratin genes, including KRT32, can lead to conditions such as palmoplantar keratoderma and other keratinization disorders. Additionally, studies have suggested that KRT32 may be involved in processes such as cell differentiation, proliferation, and response to environmental stressors. Understanding the molecular mechanisms underlying KRT32 expression and function could provide insights into therapeutic strategies for skin diseases and may enhance our knowledge of epithelial biology. Therefore, KRT32 is not only essential for basic biological research but also holds promise for clinical applications in dermatology and regenerative medicine.
