Analytical Data
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基因名
MRPL17
- Application
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别名
MRPL17; LIP2; 39S ribosomal protein L17; mitochondrial; L17mt; MRP-L17; LYST-interacting protein 2; Mitochondrial large ribosomal subunit protein bL17m
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NRX2
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表达区间
9-175 aa
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氨基酸序列
IS HGRVFRRMGL GPESRIHLLR NLLTGLVRHE RIEAPWARVD EMRGYAEKLI DYGKLGDTNE RAMRMADFWL TEKDLIPKLF QVLAPRYKDQ TGGYTRMLQI PNRSLDRAKM AVIEYKGNCL PPLPLPRRDS HLTLLNQLLQ GLRQDLRQSQ EASNHSSHTA QTPGI
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分子量
20.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Recombinant Human MRPL16 Protein，His
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Recombinant Human CABP1 Protein，His
Cat：PA2000-915DB
Protein Description
MRPL17, a member of the mitochondrial ribosomal protein family, plays a crucial role in mitochondrial protein synthesis and overall cellular metabolism. Mitochondria, often referred to as the powerhouse of the cell, are essential for ATP production and the regulation of apoptosis, making the proteins involved in their function critically important. Abnormalities in mitochondrial protein synthesis can lead to a range of diseases, including neurodegenerative disorders and cardiomyopathies. Research into MRPL17 has gained attention due to its potential implications in mitochondrial dysfunction and related pathologies. Previous studies have highlighted its role in stabilizing mitochondrial ribosomes and influencing the translation of mitochondrial mRNAs. Moreover, variations in MRPL17 expression have been implicated in various diseases, suggesting its significance as a biomarker or therapeutic target. Investigating the structural and functional aspects of MRPL17, including its interactions with other mitochondrial components, could provide insights into mitochondrial biology and aid in the development of strategies for treating mitochondrial-related diseases. Understanding MRPL17 at the molecular level not only sheds light on its specific functions but may also reveal broader mechanisms governing mitochondrial health and cellular energy dynamics. Thus, the ongoing research endeavors surrounding MRPL17 hold promise for advancing our understanding of mitochondrial biology and addressing related health challenges.
