Analytical Data
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Gene name
MRPL10
- Application
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Alternative Names
39S ribosomal protein L10; 39S ribosomal protein L10 mitochondrial; 39S ribosomal protein L10 mitochondrial precursor; 39S ribosomal protein L8; L10mt; L8mt; MGC17973; mitochondrial; Mitochondrial ribosomal protein L10; MRP L10; MRP L8; MRP-L10; MRP-L8; MRPL 10; MRPL10; MRPL8; RM10_HUMAN; RPML8
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q7Z7H8
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Expression Region
29-261 aa
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AA Sequence
GS KAVTRHRRVM HFQRQKLMAV TEYIPPKPAI HPSCLPSPPS PPQEEIGLIR LLRREIAAVF QDNRMIAVCQ NVALSAEDKL LMRHQLRKHK ILMKVFPNQV LKPFLEDSKY QNLLPLFVGH NMLLVSEEPK VKEMVRILRT VPFLPLLGGC IDDTILSRQG FINYSKLPSL PLVQGELVGG LTCLTAQTHS LLQHQPLQLT TLLDQYIREQ REKDSVMSAN GKPDPDTVPD S
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Molecular Weight
29.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MRPL10, a mitochondrial ribosomal protein, plays a crucial role in the translation of mitochondrial mRNAs, which are essential for the proper functioning of the mitochondria, the cell's energy-producing organelles. Research on MRPL10 is particularly significant as mitochondrial dysfunction is linked to various diseases, including metabolic disorders, neurodegenerative diseases, and certain types of cancer. The importance of MRPL10 in mitochondrial biogenesis and protein synthesis has raised interest in understanding its structure and function. Studies have indicated that mutations or dysregulation of MRPL10 can lead to mitochondrial diseases, highlighting its potential as a biomarker and therapeutic target. Furthermore, investigating MRPL10's interactions with other mitochondrial ribosomal proteins and its role in mitochondrial ribosome assembly can provide insights into the mechanisms of mitochondrial translation and the overall regulation of mitochondrial activity. Therefore, research on MRPL10 not only enhances our understanding of mitochondrial biology but also contributes to the development of strategies for diagnosing and treating mitochondrial-related diseases. As mitochondrial dysfunction is increasingly recognized as a key factor in many pathologies, MRPL10 emerges as a focal point for future studies aimed at unraveling the complexities of mitochondrial dynamics and their implications in health and disease.
