Analytical Data
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基因名
PFN4
- Application
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别名
PFN4;Profilin-4
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8NHR9
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表达区间
1-129aa
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氨基酸序列
MSHLQSLLLD TLLGTKHVDS AALIKIQERS LCVASPGFNV TPSDVRTLVN GFAKNPLQAR REGLYFKGKD YRCVRADEYS LYAKNENTGV VVVKTHLYLL VATYTEGMYP SICVEATESL GDYLRKKGS
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PFN4, or Profilin 4, is a member of the profilin family of actin-binding proteins, which play a crucial role in the regulation of cytoskeletal dynamics and cellular processes. Profilins are known to interact with actin monomers, facilitating their polymerization into filamentous actin, which is essential for various cellular functions such as cell motility, division, and shape maintenance. The interest in PFN4 stems from its potential involvement in both physiological and pathological processes. Recent studies have suggested that PFN4 may play a role in immune response modulation and could be involved in the progression of certain diseases, including cancer. Understanding PFN4's structure and function is key to elucidating its role in health and disease. Furthermore, PFN4's ability to interact with other proteins involved in signaling pathways emphasizes its importance in cellular communication and function. Research into PFN4 could pave the way for the development of novel therapeutic strategies targeting cytoskeletal dynamics in various diseases, particularly those related to aberrant cell behavior.
