Analytical Data
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Gene name
ADAMTSL5
- Application
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Alternative Names
ADAMTSL5；THSD6；ADAMTS-like Protein 5
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6ZMM2
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Expression Region
43-481aa
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AA Sequence
QGPGEWTPWVSWTRCSSSCGRGVSVRSRRCLRLPGEEPCWGDSHEYRLCQLPDCPPGAVPFRDLQCALYNGRPVLGTQKTYQWVPFHGAPNQCDLNCLAEGHAFYHSFGRVLDGTACSPGAQGVCVAGRCLSAGCDGLLGSGALEDRCGRCGGANDSCLFVQRVFRDAGAFAGYWNVTLIPEGARHIRVEHRSRNHLALMGGDGRYVLNGHWVVSPPGTYEAAGTHVVYTRDTGPQETLQAAGPTSHDLLLQVLLQEPNPGIEFEFWLPRERYSPFQARVQALGWPLRQPQPRGVEPQPPAAPAVTPAQTPTLAPDPCPPCPDTRGRAHRLLHYCGSDFVFQARVLGHHHQAQETRYEVRIQLVYKNRSPLRAREYVWAPGHCPCPMLAPHRDYLMAVQRLVSPDGTQDQLLLPHAGYARPWSPAEDSRIRLTARRCPG
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Molecular Weight
56.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ADAMTSL5, a member of the ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin-1 motifs) family, has garnered significant attention in recent years due to its potential roles in various physiological and pathological processes. Characterized by its unique structural features, including multiple thrombospondin motifs, ADAMTSL5 is believed to be involved in extracellular matrix interactions and may play a crucial role in tissue development, particularly in cartilage and vascular structures. Emerging evidence suggests that ADAMTSL5 is implicated in the regulation of angiogenesis and the maintenance of structural integrity in connective tissues, highlighting its importance in developmental biology and disease mechanisms such as arthritis and cancer. Moreover, studies have indicated that disruptions in ADAMTSL5 function may lead to various disorders, underscoring the necessity for comprehensive investigations. The recombinant expression of ADAMTSL5 protein offers a promising avenue for elucidating its biological functions, interactions, and regulatory mechanisms, providing insights into its potential as a therapeutic target. Understanding the enzymatic activity, protein interactions, and signaling pathways associated with ADAMTSL5 could open new avenues for therapeutic interventions in conditions where its dysregulation is evident. Thus, research on ADAMTSL5 not only enhances our comprehension of fundamental biological processes but also presents opportunities for innovative strategies in treating related diseases.
