Analytical Data
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Gene name
PLSCR4
- Application
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Alternative Names
PLSCR4；Phospholipid scramblase 4
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NRQ2
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Expression Region
1-329aa
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AA Sequence
MSGVVPTAPEQPAGEMENQTKPPDPRPDAPPEYNSHFLPGPPGTAVPPPTGYPGGLPMGYYSPQQPSTFPLYQPVGGIHPVRYQPGKYPMPNQSVPITWMPGPTPMANCPPGLEYLVQLDNIHVLQHFEPLEMMTCFETNNRYDIKNNSDQMVYIVTEDTDDFTRNAYRTLRPFVLRVTDCMGREIMTMQRPFRCTCCCFCCPSARQELEVQCPPGVTIGFVAEHWNLCRAVYSIQNEKKENVMRVRGPCSTYGCGSDSVFEVKSLDGISNIGSIIRKWNGLLSAMADADHFDIHFPLDLDVKMKAMIFGACFLIDFMYFERSPPQRSR
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Molecular Weight
37 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PLSCR4 (Phospholipid Scramblase 4) is a member of the phospholipid scramblase family, which plays a crucial role in facilitating the translocation of phospholipids between the inner and outer leaflets of the cell membrane during apoptosis and other cellular processes. As emerging research indicates, PLSCR4 is implicated in various biological functions beyond lipid scramblase activity, including immune response modulation, cell signaling, and potential roles in cancer progression. The protein's expression can be influenced by external stimuli such as cytokines and stress factors, suggesting its involvement in cellular homeostasis and pathology. Understanding the molecular mechanisms underlying PLSCR4's functions is essential for elucidating its contributions to diseases and may provide insights into novel therapeutic strategies. Given its multifaceted role in cellular regulatory processes, the study of PLSCR4 and its associated pathways is becoming increasingly relevant in the fields of cell biology, immunology, and oncology, yet many aspects of its function and regulation remain to be fully elucidated. Continued research on this protein could not only enhance our understanding of membrane dynamics but also pave the way for developing innovative interventions in diseases characterized by disrupted phospholipid sorting and cellular signaling.
