Analytical Data
-
Gene name
ABCF2
- Application
-
Alternative Names
ABCF2；ATP-binding cassette sub-family F member 2
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9UG63
-
Expression Region
1-623aa
-
AA Sequence
MPSDLAKKKA AKKKEAAKAR QRPRKGHEEN GDVVTEPQVA EKNEANGRET TEVDLLTKEL EDFEMKKAAA RAVTGVLASH PNSTDVHIIN LSLTFHGQEL LSDTKLELNS GRRYGLIGLN GIGKSMLLSA IGKREVPIPE HIDIYHLTRE MPPSDKTPLH CVMEVDTERA MLEKEAERLA HEDAECEKLM ELYERLEELD ADKAEMRASR ILHGLGFTPA MQRKKLKDFS GGWRMRVALA RALFIRPFML LLDEPTNHLD LDACVWLEEE LKTFKRILVL VSHSQDFLNG VCTNIIHMHN KKLKYYTGNY DQYVKTRLEL EENQMKRFHW EQDQIAHMKN YIARFGHGSA KLARQAQSKE KTLQKMMASG LTERVVSDKT LSFYFPPCGK IPPPVIMVQN VSFKYTKDGP CIYNNLEFGI DLDTRVALVG PNGAGKSTLL KLLTGELLPT DGMIRKHSHV KIGRYHQHLQ EQLDLDLSPL EYMMKCYPEI KEKEEMRKII GRYGLTGKQQ VSPIRNLSDG QKCRVCLAWL AWQNPHMLFL DEPTNHLDIE TIDALADAIN EFEGGMMLVS HDFRLIQQVA QEIWVCEKQT ITKWPGDILA YKEHLKSKLV DEEPQLTKRT HNV
-
Molecular Weight
71.2 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The ABCF2 protein, a member of the ATP-binding cassette (ABC) family, plays a critical role in various cellular processes, including protein translation, cellular stress responses, and the regulation of ion homeostasis. Research has shown that ABCF2 is involved in the transport of metabolites and signaling molecules across cellular membranes, impacting both normal physiological functions and pathological conditions. The interest in ABCF2 has grown due to its potential implications in diseases such as cancer, where altered expression and function of ABC transporters often correlate with multidrug resistance. Understanding ABCF2's structure, function, and regulation is essential for deciphering its role in these processes. Recent studies have utilized recombinant protein technology to produce ABCF2 in various systems, facilitating the investigation of its biochemical properties and interactions with other cellular components. This recombinant approach allows for detailed structural analysis and functional assays that are crucial for understanding how ABCF2 contributes to cellular homeostasis and disease mechanisms. As research progresses, elucidating the exact role of ABCF2 in cellular dynamics may lead to the development of targeted therapeutic strategies that leverage its function in drug transport and resistance mechanisms, thereby enhancing treatment efficacy in various diseases.
