Analytical Data
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Gene name
METTL7A
- Application
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Alternative Names
AAM B; AAMB; DKFZP586A0522; MET7A_HUMAN; Methyltransferase like 7A; Methyltransferase-like protein 7A; METTL 7A; METTL7A; METTL7A methlytransferase like 7A; Protein AAM-B; Protein AAMB
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H8H3
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Expression Region
30-244 aa
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AA Sequence
W ICKKWFPYFL VRFTVIYNEQ MASKKRELFS NLQEFAGPSG KLSLLEVGCG TGANFKFYPP GCRVTCIDPN PNFEKFLIKS IAENRHLQFE RFVVAAGENM HQVADGSVDV VVCTLVLCSV KNQERILREV CRVLRPGGAF YFMEHVAAEC STWNYFWQQV LDPAWHLLFD GCNLTRESWK ALERASFSKL KLQHIQAPLS WELVRPHIYG YAVK
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Molecular Weight
28.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
METTL7A, a member of the methyltransferase-like protein family, has garnered significant attention in recent years due to its potential roles in various biological processes and diseases. This protein is known to participate in the methylation of RNA and has been implicated in the regulation of gene expression, cellular differentiation, and stress response mechanisms. Emerging evidence suggests that METTL7A may impact cancer progression, immune responses, and viral infections, making it a promising target for therapeutic intervention. Despite these insights, the detailed biochemical properties and functional mechanisms of METTL7A remain poorly understood. Researchers are increasingly focused on producing recombinant METTL7A proteins to facilitate structural and functional studies. These recombinant proteins can be used to elucidate the substrate specificity, enzymatic activity, and molecular interactions of METTL7A, thereby providing deeper insights into its biological functions and potential pathogenic roles. Understanding the actions of METTL7A at the molecular level will not only advance our fundamental knowledge of RNA methylation processes but may also unveil novel pathways for disease treatment and prevention, particularly in oncology and virology. Overall, the study of METTL7A as a recombinant protein represents a crucial step toward uncovering its biological significance and therapeutic potential.
