Analytical Data
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Gene name
PHF11
- Application
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Alternative Names
PHF11;BCAP;PHD finger Protein 11
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UIL8
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Expression Region
1-331aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MAQASPPRPE RVLGASSPEA RPAQEALLLP TGVFQVAEKM EKRTCALCPK DVEYNVLYFA QSENIAAHEN CLLYSSGLVE CEDQDPLNPD RSFDVESVKK EIQRGRKLKC KFCHKRGATV GCDLKNCNKN YHFFCAKKDD AVPQSDGVRG IYKLLCQQHA QFPIIAQSAK FSGVKRKRGR KKPLSGNHVQ PPETMKCNTF IRQVKEEHGR HTDATVKVPF LKKCKEAGLL NYLLEEILDK VHSIPEKLMD ETTSESDYEE IGSALFDCRL FEDTFVNFQA AIEKKIHASQ QRWQQLKEEI ELLQDLKQTL CSFQENRDLM SSSTSISSLS Y
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Molecular Weight
40 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PHF11 (PHD Finger Protein 11) is a member of the PHD finger family, which plays significant roles in various biological processes, including gene regulation, chromatin remodeling, and cellular differentiation. In recent years, PHF11 has gained attention due to its involvement in immune responses and its potential link to diseases such as allergies and asthma. Researchers have identified that PHF11 can influence the function of immune cells, particularly T cells and mast cells, thus potentially contributing to the pathogenesis of atopic diseases. The interest in PHF11 extends to its role in epigenetic mechanisms, where its PHD finger domain can interact with histones and contribute to gene expression regulation. This creates a compelling case for studying PHF11 as a target for therapeutic interventions in immune-mediated disorders. The generation of recombinant PHF11 proteins in vitro allows scientists to investigate its biochemical properties, interaction partners, and functional roles in cellular contexts. Understanding the exact mechanisms by which PHF11 operates can pave the way for novel strategies to modulate immune responses, ultimately enhancing treatment options for conditions linked to dysregulated immune function. Furthermore, the recombinant proteins serve as valuable tools for high-throughput screening in drug development, making PHF11 a focal point for research aiming to unravel its contributions to health and disease.
