Analytical Data
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Gene name
PHF13
- Application
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Alternative Names
PHF13;PHD finger Protein 13
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q86YI8
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Expression Region
1-300aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMDSDSCA AAFHPEEYSP SCKRRRTVED FNKFCTFVLA YAGYIPYPKE ELPLRSSPSP ANSTAGTIDS DGWDAGFSDI ASSVPLPVSD RCFSHLQPTL LQRAKPSNFL LDRKKTDKLK KKKKRKRRDS DAPGKEGYRG GLLKLEAADP YVETPTSPTL QDIPQAPSDP CSGWDSDTPS SGSCATVSPD QVKEIKTEGK RTIVRQGKQV VFRDEDSTGN DEDIMVDSDD DSWDLVTCFC MKPFAGRPMI ECNECHTWIH LSCAKIRKSN VPEVFVCQKC RDSKFDIRRS NRSRTGSRKL FLD
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Molecular Weight
36 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PHF13, or PHD finger protein 13, is a member of the plant homeodomain (PHD) finger family, which plays critical roles in chromatin remodeling and gene regulation. Recent studies have highlighted PHF13's involvement in various biological processes, including cell proliferation, differentiation, and apoptosis, making it a significant focus in cancer research. The protein is known to interact with numerous partners and is implicated in the regulation of several oncogenes and tumor suppressor genes. Understanding the structure and function of recombinantly expressed PHF13 can provide insights into its mechanisms of action and its role in disease pathogenesis. Furthermore, the potential for PHF13 as a therapeutic target or biomarker in cancer treatment adds an intriguing dimension to its study. Research into PHF13 includes the generation of recombinant proteins to better characterize their interactions and functional roles, paving the way for novel therapeutic strategies. The reconstituted protein not only facilitates high-throughput screenings for drug discovery but also assists in elucidating the signaling pathways influenced by PHF13, thus contributing to a deeper understanding of its biological significance.
