Analytical Data
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基因名
MEI1
- Application
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别名
MEI1Meiosis inhibitor protein 1; Meiosis defective protein 1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q5TIA1
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表达区间
1-238aa
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氨基酸序列
MLALTLAKADSPRTALLCSAWLLTASFSAQQHKGSLQVHQTLSVEMDQVLKALSFPKKKAALLSAAILCFLRTALRQSFSSALVALVPSGAQPLPATKDTVLAPLRMSQVRSLVIGLQNLLVQKDPLLSQACVGCLEALLDYLDARSPDIALHVASQPWNRFLLFTLLDAGENSFLRPEILRLMTLLQSMGHLADHSMAQTLQASLEGLPPSTSSGQPPLQDMLCLGGVAVSLSHIRN
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分子量
52 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MEI1 is a crucial protein involved in the regulation of meiotic recombination, a process essential for the formation of gametes in many organisms. In recent years, there has been a growing interest in understanding the molecular mechanisms underlying meiosis, particularly how meiotic recombination is orchestrated to ensure genetic diversity and stability. MEI1 has been identified as a key player in the assembly of the synaptonemal complex, which is vital for homologous chromosome pairing and recombination during meiosis. Its role in promoting the selection of homologous chromosomes and preventing inappropriate recombination events is critical for successful gametogenesis. Given the importance of reproductive success in both agriculture and conservation, research into MEI1 and its functional dynamics may provide insights into fertility issues, genetic disorders, and potential biotechnological applications in crop improvement. Recent studies have explored MEI1's interaction with other proteins and its regulation by post-translational modifications, shedding light on the intricate network that governs meiotic progression. Understanding MEI1's biochemical pathways will not only elucidate fundamental biological processes but also potentially lead to advancements in reproductive health and agricultural biotechnology by manipulating meiotic behavior for better yield and genetic outcomes.
