Analytical Data
-
Gene name
PLSCR5
- Application
-
Alternative Names
PLSCR5；Phospholipid scramblase family member 5
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
A0PG75
-
Expression Region
1-271aa
-
AA Sequence
MASKDAQNQR RGLPGFLPGA PDPDQSLPAS SNPGNQAWQL SLPLPSSFLP TVSLPPGLEY LSQLDLIIIH QQVELLGMIL GTETSNKYEI KNSLGQRIYF AVEESICFNR TFCSTLRSCT LRITDNSGRE VITVNRPLRC NSCWCPCYLQ ELEIQAPPGT IVGYVTQKWD PFLPKFTIQN ANKEDILKIV GPCVTCGCFG DVDFEVKTIN EKLTIGKISK YWSGFVNDVF TNADNFGIHV PADLDVTVKA AMIGACFLFD FMFFEHSLAG L
-
Molecular Weight
30.0 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PLSCR5 (Phospholipid Scramblase 5) is a member of the scramblase family of proteins that play a crucial role in the disruption and translocation of phospholipids between the inner and outer leaflets of the cell membrane. This protein is involved in various physiological processes, including membrane dynamics, apoptosis, and platelet activation. Research has indicated that PLSCR5 contributes to the regulation of phosphatidylserine exposure on the cell surface, a key event in apoptosis that signals macrophages for clearance of dead or dying cells. Furthermore, aberrations in PLSCR5 expression and function have been linked to several pathological conditions, including cancer and cardiovascular diseases. Given its significant role in membrane biology and cell signaling, PLSCR5 has become a focal point for understanding cell fate decisions and the mechanisms of cell death. Recent studies have aimed to elucidate its structural and functional properties through recombinant protein techniques, enabling researchers to investigate its mechanisms of action and potential as a therapeutic target. By studying PLSCR5, scientists hope to uncover novel pathways involved in disease progression and identify new strategies for intervention, making it an important protein in the realm of biomedical research.
