Cat: PA2000-5046

Recombinant Human Tsku Protein,His

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Analytical Data

  • Gene name

    Tsku

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Tsku;E2IG4;LRRC54;TSK;Tsukushi

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8WUA8

  • Expression Region

    17-353

  • AA Sequence

    TRPC FPGCQCEVET FGLFDSFSLT RVDCSGLGPH IMPVPIPLDT AHLDLSSNRL EMVNESVLAG PGYTTLAGLD LSHNLLTSIS PTAFSRLRYL ESLDLSHNGL TALPAESFTS SPLSDVNLSH NQLREVSVSA FTTHSQGRAL HVDLSHNLIH RLVPHPTRAG LPAPTIQSLN LAWNRLHAVP NLRDLPLRYL SLDGNPLAVI GPGAFAGLGG LTHLSLASLQ RLPELAPSGF RELPGLQVLD LSGNPKLNWA GAEVFSGLSS LQELDLSGTN LVPLPEALLL HLPALQSVSV GQDVRCRRLV REGTYPRRPG SSPKVALHCV DTRDSAARGP TIL

  • Molecular Weight

    37.8kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

Tsku, a member of the TGF-β superfamily, is a protein that plays a crucial role in various biological processes, including cell proliferation, differentiation, and extracellular matrix regulation. Historically, research into Tsku has focused on its involvement in developmental biology and its potential implications in tissue regeneration and repair. Recent studies have revealed that Tsku exhibits significant affinity for specific cellular receptors, indicating its vital role in mediating cellular signaling pathways. This has generated interest in Tsku as a potential therapeutic target for diseases characterized by aberrant signaling mechanisms, such as cancer and fibrosis. The recombinant expression of Tsku has enabled researchers to produce this protein in vitro, facilitating detailed investigations into its biochemical properties and biological functions. By understanding the structure-function relationships of recombinant Tsku, scientists aim to elucidate its role in health and disease, paving the way for innovative therapeutic strategies. Moreover, Tsku's potential applications in regenerative medicine and biotechnology underscore the importance of continued research in this field, with the hope of harnessing its properties for therapeutic uses.

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