Analytical Data
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Gene name
CAPN9
- Application
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Alternative Names
CAPN9；NCL4；Calpain-9
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O14815
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Expression Region
1-690aa
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AA Sequence
MPYLYRAPGP QAHPVPKDAR ITHSSGQSFE QMRQECLQRG TLFEDADFPA SNSSLFYSER PQIPFVWKRP GEIVKNPEFI LGGATRTDIC QGELGDCWLL AAIASLTLNQ KALARVIPQD QSFGPGYAGI FHFQFWQHSE WLDVVIDDRL PTFRDRLVFL HSADHNEFWS ALLEKAYAKL NGSYEALKGG SAIEAMEDFT GGVAETFQTK EAPENFYEIL EKALKRGSLL GCFIDTRSAA ESEARTPFGL IKGHAYSVTG IDQVSFRGQR IELIRIRNPW GQVEWNGSWS DSSPEWRSVG PAEQKRLCHT ALDDGEFWMA FKDFKAHFDK VEICNLTPDA LEEDAIHKWE VTVHQGSWVR GSTAGGCRNF LDTFWTNPQI KLSLTEKDEG QEECSFLVAL MQKDRRKLKR FGANVLTIGY AIYECPDKDE HLNKDFFRYH ASRARSKTFI NLREVSDRFK LPPGEYILIP STFEPHQEAD FCLRIFSEKK AITRDMDGNV DIDLPEPPKP TPPDQETEEE QRFRALFEQV AGEDMEVTAE ELEYVLNAVL QKKKDIKFKK LSLISCKNII SLMDTSGNGK LEFDEFKVFW DKLKQWINLF LRFDADKSGT MSTYELRTAL KAAGFQLSSH LLQLIVLRYA DEELQLDFDD FLNCLVRLEN ASRVFQALST KNKEFIHLNI NEFIHLTMNI
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Molecular Weight
79 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CAPN9, a member of the calpain family, is a calcium-dependent cysteine protease that plays a critical role in various cellular processes, including cell differentiation, apoptosis, and migration. Its unique expression pattern, predominantly in digestive tissues, suggests it may be involved in gastrointestinal physiology and pathology. Recent studies have indicated that CAPN9 could be linked to certain cancers, particularly those of the digestive system, highlighting its potential as a biomarker for disease progression and a target for therapeutic intervention. Research into the recombinant expression of CAPN9 has gained momentum as scientists aim to elucidate its functional mechanisms and interactions within cellular environments. By producing recombinant CAPN9, researchers can investigate its enzymatic activity, substrate specificity, and regulatory mechanisms in detail. Furthermore, exploring the role of CAPN9 in signaling pathways may provide insights into its contribution to tumorigenesis and tissue homeostasis. Understanding the structural and functional characteristics of CAPN9 through recombinant technology could pave the way for novel diagnostic and therapeutic strategies, potentially improving outcomes in cancer patients. Overall, the study of CAPN9 not only enhances our comprehension of calpain family members but also holds promise for advancing medical research and therapeutic approaches in the context of gastrointestinal disorders.
