Analytical Data
-
Gene name
MBOAT1
- Application
-
Alternative Names
MBOAT1; OACT1Lysophospholipid acyltransferase 1; LPLAT 1; EC 2.3.1.-; 1-acylglycerophosphoserine O-acyltransferase; EC 2.3.1.n6; Lysophosphatidylserine acyltransferase; LPSAT; Lyso-PS acyltransferase; Membrane-bound O-acyltransferase domain-containing protein 1; O-acyltransferase domain-containing protein 1
-
Species
Human
-
Source
E. coli
-
Tag
GST-tag at N-terminal
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q6ZNC8
-
Expression Region
1-371aa
-
AA Sequence
MAAEPQPSSLSYRTTGSTYLHPLSELLGIPLDQVNFVVCQLVALFAAFWFRIYLRPGTTSSDVRHAVATIFGIYFVIFCFGWYSVHLFVLVLMCYAIMVTASVSNIHRYSFFVAMGYLTICHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSAEQHRLAIKVKPSFLEYLSYLLNFMSVIAGPCNNFKDYIAFIEGKHIHMKLLEVNWKRKGFHSLPEPSPTGAVIHKLGITLVSLLLFLTLTKTFPVTCLVDDWFVHKASFPARLCYLYVVMQASKPKYYFAWTLADAVNNAAGFGFSGVDKNGNFCWDLLSNLNIWKIETATSFKMYLENWNIQTATWLKCVCYQRVHGTPRC
-
Molecular Weight
68.6 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MBOAT1 (Membrane-Bound O-acyltransferase Domain-Containing Protein 1) is a crucial enzyme implicated in lipid metabolism, particularly in the acylation of lysophospholipids, which plays a vital role in membrane composition and signaling pathways. Dysregulation of MBOAT1 has been linked to various diseases, including cancer and metabolic disorders, making it a significant target for therapeutic interventions. The study of MBOAT1's structure and function is essential to understand its role in health and disease. Recent advances in protein engineering and recombinant DNA technology enable the production of MBOAT1 as a recombinant protein, facilitating in-depth biochemical assays and structural studies. Such research aims to elucidate the enzymatic mechanisms of MBOAT1, its interaction with other cellular components, and its impact on lipid-mediated signaling pathways. Understanding MBOAT1's activity and regulation could have profound implications for developing novel strategies to tackle diseases associated with lipid metabolism. By characterizing MBOAT1, researchers seek to uncover potential biomarkers for diagnostic purposes and to identify inhibitors that could serve as therapeutic agents, thereby highlighting the significance of MBOAT1 in biomedical research and its potential utility in clinical applications.
