Analytical Data
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基因名
MBOAT1
- Application
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别名
MBOAT1; OACT1Lysophospholipid acyltransferase 1; LPLAT 1; EC 2.3.1.-; 1-acylglycerophosphoserine O-acyltransferase; EC 2.3.1.n6; Lysophosphatidylserine acyltransferase; LPSAT; Lyso-PS acyltransferase; Membrane-bound O-acyltransferase domain-containing protein 1; O-acyltransferase domain-containing protein 1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6ZNC8
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表达区间
1-371aa
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氨基酸序列
MAAEPQPSSLSYRTTGSTYLHPLSELLGIPLDQVNFVVCQLVALFAAFWFRIYLRPGTTSSDVRHAVATIFGIYFVIFCFGWYSVHLFVLVLMCYAIMVTASVSNIHRYSFFVAMGYLTICHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSAEQHRLAIKVKPSFLEYLSYLLNFMSVIAGPCNNFKDYIAFIEGKHIHMKLLEVNWKRKGFHSLPEPSPTGAVIHKLGITLVSLLLFLTLTKTFPVTCLVDDWFVHKASFPARLCYLYVVMQASKPKYYFAWTLADAVNNAAGFGFSGVDKNGNFCWDLLSNLNIWKIETATSFKMYLENWNIQTATWLKCVCYQRVHGTPRC
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分子量
68.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MBOAT1 (Membrane-Bound O-acyltransferase Domain-Containing Protein 1) is a crucial enzyme implicated in lipid metabolism, particularly in the acylation of lysophospholipids, which plays a vital role in membrane composition and signaling pathways. Dysregulation of MBOAT1 has been linked to various diseases, including cancer and metabolic disorders, making it a significant target for therapeutic interventions. The study of MBOAT1's structure and function is essential to understand its role in health and disease. Recent advances in protein engineering and recombinant DNA technology enable the production of MBOAT1 as a recombinant protein, facilitating in-depth biochemical assays and structural studies. Such research aims to elucidate the enzymatic mechanisms of MBOAT1, its interaction with other cellular components, and its impact on lipid-mediated signaling pathways. Understanding MBOAT1's activity and regulation could have profound implications for developing novel strategies to tackle diseases associated with lipid metabolism. By characterizing MBOAT1, researchers seek to uncover potential biomarkers for diagnostic purposes and to identify inhibitors that could serve as therapeutic agents, thereby highlighting the significance of MBOAT1 in biomedical research and its potential utility in clinical applications.
