Analytical Data
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基因名
DEFa2
- Application
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别名
DEFa2;DEF1;DEFA2;MRS;Neutrophil defensin 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P59665
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表达区间
1-94aa
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氨基酸序列
MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGSRKNMACYCRIPACIAGERRYGTCIYQGRLWAFCC
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分子量
37.2kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
DEFa2, a member of the defensin family, plays a vital role in the innate immune response. Defensins are small cationic peptides that exhibit antimicrobial activity against a broad range of pathogens, including bacteria, fungi, and viruses. Research into DEFa2 has gained momentum due to its potential therapeutic applications and its role in host defense mechanisms. Emerging studies have shown that DEFa2 possesses not only direct antimicrobial properties but also regulatory functions in immune modulation, influencing processes such as inflammation and wound healing. Understanding the structural characteristics and functional mechanisms of DEFa2 is crucial for developing novel antimicrobial agents, particularly in the face of rising antibiotic resistance. Moreover, DEFa2's involvement in various physiological and pathological processes highlights its significance in health and disease. As a recombinant protein, DEFa2 can be engineered and produced for detailed biochemical and biophysical studies, paving the way for its application in drug development and therapeutic interventions. Overall, the ongoing research on DEFa2 not only enhances our knowledge of host-pathogen interactions but also opens new avenues for innovative treatments targeting infectious diseases.












