Analytical Data
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Gene name
NPPC
- Application
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Alternative Names
NPPC;CNP2;C-type natriuretic peptide
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P23582
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Expression Region
24-126aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSKPGAPPK VPRTPPAEEL AEPQAAGGGQ KKGDKAPGGG GANLKGDRSR LLRDLRVDTK SRAAWARLLQ EHPNARKYKG ANKKGLSKGC FGLKLDRIGS MSGLGC
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Molecular Weight
13 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of NPPC (Natriuretic Peptide Precursor C) recombinant proteins has gained significant attention due to their crucial role in cardiovascular health and disease. NPPC is a member of the natriuretic peptide family, involved in regulating blood pressure, fluid balance, and cardiac function. It is primarily synthesized in the heart's ventricles and acts as a potent vasodilator, promoting the excretion of sodium and water, and thereby influencing cardiac remodeling and hypertrophy. Recent advancements in recombinant DNA technology have enabled the production of NPPC in various systems, allowing researchers to explore its therapeutic potential more thoroughly. This includes investigating its protective roles against heart failure, hypertension, and other cardiovascular disorders. The development of NPPC as a therapeutic agent also hinges on understanding its structure-function relationship, post-translational modifications, and mode of action. Furthermore, as the prevalence of cardiovascular diseases continues to rise globally, there is an urgent need for novel and effective treatments. Consequently, NPPC recombinant protein research not only provides insights into the fundamental mechanisms of cardiovascular physiology but also opens avenues for innovative therapeutic strategies aimed at improving patient outcomes in heart disease. By elucidating the biological functions of NPPC and harnessing its properties through recombinant technology, researchers aim to develop new diagnostic markers and targeted therapies that may revolutionize the management of cardiovascular conditions.
