Analytical Data
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基因名
NPPC
- Application
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别名
NPPC;CNP2;C-type natriuretic peptide
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P23582
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表达区间
24-126aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSKPGAPPK VPRTPPAEEL AEPQAAGGGQ KKGDKAPGGG GANLKGDRSR LLRDLRVDTK SRAAWARLLQ EHPNARKYKG ANKKGLSKGC FGLKLDRIGS MSGLGC
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分子量
13 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of NPPC (Natriuretic Peptide Precursor C) recombinant proteins has gained significant attention due to their crucial role in cardiovascular health and disease. NPPC is a member of the natriuretic peptide family, involved in regulating blood pressure, fluid balance, and cardiac function. It is primarily synthesized in the heart's ventricles and acts as a potent vasodilator, promoting the excretion of sodium and water, and thereby influencing cardiac remodeling and hypertrophy. Recent advancements in recombinant DNA technology have enabled the production of NPPC in various systems, allowing researchers to explore its therapeutic potential more thoroughly. This includes investigating its protective roles against heart failure, hypertension, and other cardiovascular disorders. The development of NPPC as a therapeutic agent also hinges on understanding its structure-function relationship, post-translational modifications, and mode of action. Furthermore, as the prevalence of cardiovascular diseases continues to rise globally, there is an urgent need for novel and effective treatments. Consequently, NPPC recombinant protein research not only provides insights into the fundamental mechanisms of cardiovascular physiology but also opens avenues for innovative therapeutic strategies aimed at improving patient outcomes in heart disease. By elucidating the biological functions of NPPC and harnessing its properties through recombinant technology, researchers aim to develop new diagnostic markers and targeted therapies that may revolutionize the management of cardiovascular conditions.












